The skin is the human body's largest organ and serves as a crucial boundary between the
body and the external environment. As a natural process, skin aging cannot be avoided, and …

Hydrogels are a class of highly absorbent and easily modified polymer materials suitable for
use as slow-release carriers for drugs. Gene therapy is highly specific and can overcome the …

Human 5-lipoxygenase (5-LOX) and cyclooxygenase-2 (COX-2) are potential targets for
suppressing pruritic skin inflammation in atopic dermatitis (AD). In addition, Staphylococcus …

Microneedles invade skin tissue in a minimally invasive manner, with a small traumatic
surface and slight pain. There is growing interest in the potential application of microneedle …

In recent decades, the development and application of cell culture platforms has emerged as
a promising interdisciplinary field to address critical challenges in tissue engineering and …

In vitro three-dimensional (3D) biomimetic epidermal tissue is a human skin equivalent
developed based on the 3R principle (replacement, reduction, and refinement), which has …

Novel drug delivery technologies and knowledge of skin anatomy have been revolutionary
in healthcare. This chapter explores the intricate structure of the skin and the use of …