[HTML][HTML] Recent advances progress of targeted drugs combined with radiotherapy for advanced non-small cell lung cancer: a review

J Xu, Z Wang - Frontiers in Oncology, 2023 - frontiersin.org
Targeted drug therapy plays an important role in the clinical application of non-small cell
lung cancer, especially adenocarcinoma. However, for patients with advanced disease, drug …

[HTML][HTML] Efficacy and safety of apatinib combined with whole-brain radiation therapy with a simultaneous integrated boost for brain metastases from non-small cell lung …

J Ma, J Bi, X Tuo, G Pi, Y Li, Y Li, F Zeng… - Journal of Thoracic …, 2022 - ncbi.nlm.nih.gov
Background Brain metastases (BMs) develop in 20–65% of non-small cell lung cancer
(NSCLC) patients and are associated with a poor prognosis. Apatinib, a tyrosine kinase …

[HTML][HTML] Clinical study on the safety, efficacy, and prognosis of molecular targeted drug therapy for advanced gastric cancer

L Wang, W Li, Y Liu, C Zhang, W Gao… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Objective: To investigate the safety, efficacy, and prognosis of advanced gastric cancer
patients treated with molecular targeted drug therapy. Methods: A total of 200 patients with …

Continuous low-dose apatinib combined with WBRT significantly reduces peritumoral edema and enhances the efficacy of symptomatic multiple brain metastases in …

Y Ren, SB Wang, L Zhou, SQ Liu… - … in Cancer Research …, 2021 - journals.sagepub.com
Background: Symptomatic multiple brain metastases with peritumoral brain edema (PTBE)
occur in non-small cell lung cancer patients (NSCLC) who are without driver mutations or …

[HTML][HTML] 肺癌脑转移的放射治疗

李媛媛, 赵红 - Advances in Clinical Medicine, 2023 - hanspub.org
肺癌是脑转移瘤(brain metastases, BM) 最常见的原发肿瘤, 大约40% 的肺癌患者将在整个病程
中发展为脑转移, 肺癌患者在诊断为脑转移后存活率显著下降. 历史上, 全脑放射治疗(WBRT) …

[HTML][HTML] Effect of X-ray radiation on the pharmacokinetics of apatinib in vivo in rats

SQ Dong, F Yang, DX Zhang, LM Wang… - Frontiers in …, 2022 - frontiersin.org
Purpose: The “radiotherapy-pharmacokinetic”(“RT-PK”) phenomenon refers to the fact that
radiation can significantly alter the pharmacokinetic behavior of a drug. At present, it is not …