Biomaterials have played an increasingly prominent role in the success of biomedical
devices and in the development of tissue engineering, which seeks to unlock the …

The extracellular matrix (ECM) is a heterogeneous, connective network composed of fibrous
glycoproteins that coordinate in vivo to provide the physical scaffolding, mechanical stability …

The advent of more potent immunosuppressants led to the first successful human upper
extremity transplantation in 1998. At this time,> 100 upper extremity transplants, 30 face …

Hand and upper extremity transplantation (HUET) has emerged as the most frequently
performed reconstructive procedure in the burgeoning field of vascularized composite …

The first facial transplantation in 2005 ushered in a new era in reconstructive surgery,
offering new possibilities for the repair of severe disfigurements previously limited by …

In the 30 years since the rabbit antithymocyte globulin (rATG) Thymoglobulin® was first
licensed, its use in solid organ transplantation and hematology has expanded progressively …

Background For 50 years, static cold storage (SCS) has been the gold standard for solid
organ preservation in transplantation. Although logistically convenient, this preservation …

and ethical questions remain regarding the psychosocial ramifications of the procedure. This
article reviews the literature on the different roles of the face as well as psychological and …

Vascularized composite allograft (VCA) transplantation has emerged as a groundbreaking
surgical intervention to return identity and function following traumatic injury, congenital …

Background In vascularized composite allotransplantation, multiple types of tissue are
transferred from donor to recipient as a single functional unit. This technique has been …