Bacteria in cancer initiation, promotion and progression

G El Tekle, WS Garrett - Nature Reviews Cancer, 2023 - nature.com
Cancer cells originate from a series of acquired genetic mutations that can drive their
uncontrolled cell proliferation and immune evasion. Environmental factors, including the …

[HTML][HTML] Association between periodontal pathogens and systemic disease

FQ Bui, CLC Almeida-da-Silva, B Huynh, A Trinh, J Liu… - Biomedical journal, 2019 - Elsevier
A growing body of literature suggests that there is a link between periodontitis and systemic
diseases. These diseases include cardiovascular disease, gastrointestinal and colorectal …

The role of gut microbiota in cancer treatment: friend or foe?

WY Cheng, CY Wu, J Yu - Gut, 2020 - gut.bmj.com
The gut microbiota has been implicated in cancer and shown to modulate anticancer drug
efficacy. Altered gut microbiota is associated with resistance to chemo drugs or immune …

Gut microbiota, inflammation, and colorectal cancer

CA Brennan, WS Garrett - Annual review of microbiology, 2016 - annualreviews.org
Colorectal cancer is the second-leading cause of cancer-related deaths in the United States
and fourth-leading cause of cancer-related deaths worldwide. While cancer is largely …

Immunomodulatory potential of gut microbiome-derived short-chain fatty acids (SCFAs)

W Ratajczak, A Rył, A Mizerski… - Acta Biochimica …, 2019 - abp.ptbioch.edu.pl
Intestinal microbiota is an element of the bacterial ecosystem in all mammalian organisms.
These microorganisms play a very important part in the development, functioning, and …

Human Colon Cancer–Derived Clostridioides difficile Strains Drive Colonic Tumorigenesis in Mice

JL Drewes, J Chen, NO Markham, RJ Knippel… - Cancer discovery, 2022 - AACR
Defining the complex role of the microbiome in colorectal cancer and the discovery of novel,
protumorigenic microbes are areas of active investigation. In the present study, culturing and …

[HTML][HTML] Fusobacterium nucleatum and colorectal cancer: A review

FM Shang, HL Liu - World journal of gastrointestinal oncology, 2018 - ncbi.nlm.nih.gov
Fusobacterium nucleatum (F. nucleatum) is a Gram-negative obligate anaerobe bacterium
in the oral cavity and plays a role in several oral diseases, including periodontitis and …

Increased Abundance of Clostridium and Fusobacterium in Gastric Microbiota of Patients with Gastric Cancer in Taiwan

YY Hsieh, SY Tung, HY Pan, CW Yen, HW Xu, YJ Lin… - Scientific reports, 2018 - nature.com
Helicobacter pylori is recognised as a main risk factor for gastric cancer. However,
approximately half of the patients with gastritis are negative for H. pylori infection, and the …

Colon carcinogenesis: the interplay between diet and gut microbiota

YL Loke, MT Chew, YF Ngeow, WWD Lim… - Frontiers in cellular and …, 2020 - frontiersin.org
Colorectal cancer (CRC) incidence increases yearly, and is three to four times higher in
developed countries compared to developing countries. The well-known risk factors have …

Stunted childhood growth is associated with decompartmentalization of the gastrointestinal tract and overgrowth of oropharyngeal taxa

P Vonaesch, E Morien… - Proceedings of the …, 2018 - National Acad Sciences
Linear growth delay (stunting) affects roughly 155 million children under the age of 5 years
worldwide. Treatment has been limited by a lack of understanding of the underlying …