Hintergrund Generell gilt, dass von der Nierenfunktion wichtige Therapieentscheidungen
abhängen, weshalb ihrer korrekten Bestimmung große Bedeutung zukommt. Dies spielt …

Physiologically based pharmacokinetic models (PBPK) provide an in silico framework that
integrates biological, drug, and trial design information to predict drug fate. Information on …

Based on a population pharmacokinetic model, Sinnappah et al. 1 have recently suggested
that oral metformin HCl doses of 250–500 mg post-dialysis or 250 mg daily should be safe to …

Adverse drug reactions depict one of the leading causes of death in developed countries
and can often be attributed to drug-drug, drug-gene and drug-disease interactions …

Metformin-Cimetidine Drug Interaction and Risk of Lactic Acidosis in Renal Failure: A
Pharmacovigilance-Pharmacokinetic Appraisa Page 1 Metformin-Cimetidine Drug Interaction …

Metformin is one of the most widely prescribed medications for the treatment of type 2
diabetes (T2DM) but metformin response varies greatly between individuals, polymorphisms …

Adverse drug reactions depict one of the leading causes of death in developed countries
and can often be attributed to drug-drug, druggene and drug-disease interactions. However …

博士論文 Quantitative analysis of drug-drug interaction in chronic kidney disease patients
using endogenous transporter biom Page 1 1 博士論文 Quantitative analysis of drug-drug …