Global perspectives on resilience in children and youth

AS Masten - Child development, 2014 - Wiley Online Library
Global concerns about the consequences of disasters, political violence, disease,
malnutrition, maltreatment, and other threats to human development and well‐being have …

Mechanisms underlying the effects of prenatal psychosocial stress on child outcomes: beyond the HPA axis

R Beijers, JK Buitelaar, C de Weerth - European child & adolescent …, 2014 - Springer
Accumulating evidence from preclinical and clinical studies indicates that maternal
psychosocial stress and anxiety during pregnancy adversely affect child outcomes …

Two-step epigenetic Mendelian randomization: a strategy for establishing the causal role of epigenetic processes in pathways to disease

CL Relton, G Davey Smith - International journal of …, 2012 - academic.oup.com
The burgeoning interest in the field of epigenetics has precipitated the need to develop
approaches to strengthen causal inference when considering the role of epigenetic …

[HTML][HTML] Environmental epigenetic transgenerational inheritance and somatic epigenetic mitotic stability

MK Skinner - Epigenetics, 2011 - ncbi.nlm.nih.gov
The majority of environmental factors can not modify DNA sequence, but can influence the
epigenome. The mitotic stability of the epigenome and ability of environmental epigenetics …

Endocrine disruptor induction of epigenetic transgenerational inheritance of disease

MK Skinner - Molecular and cellular endocrinology, 2014 - Elsevier
Environmental exposures such as toxicants, nutrition and stress have been shown to
promote the epigenetic transgenerational inheritance of disease susceptibility. Endocrine …

Sex differences in the programming effects of prenatal stress on psychopathology and stress responses: an evolutionary perspective

V Glover, J Hill - Physiology & behavior, 2012 - Elsevier
There is strong evidence from animal studies that prenatal stress has different effects on
male and female offspring. In general, although not always, prenatal stress increases …

[HTML][HTML] Environmental stress and epigenetic transgenerational inheritance

MK Skinner - BMC medicine, 2014 - Springer
Previous studies have shown a wide variety of environmental toxicants and abnormal
nutrition can promote the epigenetic transgenerational inheritance of disease. More recently …

[HTML][HTML] Maternal stress induces epigenetic signatures of psychiatric and neurological diseases in the offspring

FCR Zucchi, Y Yao, ID Ward, Y Ilnytskyy, DM Olson… - PloS one, 2013 - journals.plos.org
The gestational state is a period of particular vulnerability to diseases that affect maternal
and fetal health. Stress during gestation may represent a powerful influence on maternal …

Early-life glucocorticoid exposure: the hypothalamic-pituitary-adrenal axis, placental function, and long-term disease risk

T Braun, JR Challis, JP Newnham… - Endocrine …, 2013 - academic.oup.com
An adverse early-life environment is associated with long-term disease consequences.
Adversity early in life is hypothesized to elicit developmental adaptations that serve to …

Development and the epigenome: the 'synapse'of gene–environment interplay

WT Boyce, MS Kobor - Developmental science, 2015 - Wiley Online Library
This paper argues that there is a revolution afoot in the developmental science of gene–
environment interplay. We summarize, for an audience of developmental researchers and …