[HTML][HTML] Biomaterials for nanoparticle vaccine delivery systems

P Sahdev, LJ Ochyl, JJ Moon - Pharmaceutical research, 2014 - Springer
Subunit vaccination benefits from improved safety over attenuated or inactivated vaccines,
but their limited capability to elicit long-lasting, concerted cellular and humoral immune …

Current advances in self-assembled nanogel delivery systems for immunotherapy

Y Tahara, K Akiyoshi - Advanced drug delivery reviews, 2015 - Elsevier
Since nanogels (nanometer-sized gels) were developed two decades ago, they were
utilized as carriers of innovative drug delivery systems. In particular, immunological drug …

Poly-γ-glutamic acid nanoparticles as adjuvant and antigen carrier system for cancer vaccination

V Mohammadzadeh, N Rahiman, H Cabral… - Journal of Controlled …, 2023 - Elsevier
Vaccination is an innovative strategy for cancer treatment by leveraging various components
of the patients' immunity to boost an anti-tumor immune response. Rationally designed …

Polymers for subunit vaccine delivery

RJ Nevagi, M Skwarczynski, I Toth - European Polymer Journal, 2019 - Elsevier
Mimicking the size and structural features of a pathogen is critical in developing immunity
through subunit vaccines; it has been shown that this can be successfully achieved by nano …

Nanoparticle‐based manipulation of antigen‐presenting cells for cancer immunotherapy

RH Fang, AV Kroll, L Zhang - Small, 2015 - Wiley Online Library
Immunotherapeutic approaches for treating cancer overall have been receiving a
considerable amount of interest due to the recent approval of several clinical formulations …

Biodegradable polymers for modern vaccine development

RJC Bose, M Kim, JH Chang, R Paulmurugan… - Journal of Industrial and …, 2019 - Elsevier
Most traditional vaccines are composed either of a whole pathogen or its parts; these
vaccines, however, are not always effective and can even be harmful. As such, additional …

[HTML][HTML] Nanoparticle cancer vaccines: Design considerations and recent advances

J Liu, L Miao, J Sui, Y Hao, G Huang - Asian Journal of Pharmaceutical …, 2020 - Elsevier
Vaccines therapeutics manipulate host's immune system and have broad potential for
cancer prevention and treatment. However, due to poor immunogenicity and limited safety …

Polymeric nanogels as vaccine delivery systems

SA Ferreira, FM Gama, M Vilanova - … : Nanotechnology, Biology and …, 2013 - Elsevier
Polymeric nanogels find a relevant field of application in the formulation of a new generation
of therapeutic and preventive vaccines, aiming at the fine-tuned modulation of the immune …

Applications of polymeric adjuvants in studying autoimmune responses and vaccination against infectious diseases

AK Shakya, KS Nandakumar - Journal of the Royal …, 2013 - royalsocietypublishing.org
Polymers as an adjuvant are capable of enhancing the vaccine potential against various
infectious diseases and also are being used to study the actual autoimmune responses …

[HTML][HTML] Modifying antigen-encapsulating liposomes with KALA facilitates MHC class I antigen presentation and enhances anti-tumor effects

N Miura, H Akita, N Tateshita, T Nakamura… - Molecular therapy, 2017 - cell.com
For a successful anti-cancer vaccine, antigen presentation on the major histocompatibility
complex (MHC) class I is a requirement. To accomplish this, an antigen must be delivered to …