Background Male infertility is a widespread condition among couples. In about 50% of
cases, couple infertility is attributable to the male partner, mainly due to a failure in …

Adolescence is a period of biological, psychological and social changes, and the peak time
for the emergence of mental health problems. During this life stage, brain plasticity including …

AMPK activated protein kinase (AMPK), a master regulator of energy homeostasis, is
activated in response to an energy shortage imposed by physical activity and caloric …

The modern lifestyle has a negative impact on health. It is usually accompanied by
increased stress levels and lower physical activity, which interferes with body homeostasis …

Background/Aims: Regular physical exercise can enhance resistance to many microbial
infections. However, little is known about the mechanism underlying the changes in the …

New Findings What is the topic of this review? This review discusses the evidence of the
benefits of exercise training for β‐cell health through improvements in function, proliferation …

Pancreatic beta cells sense glucose flux and release as much insulin as required in order to
maintain glycaemia within a narrow range. Insulin secretion is regulated by many factors …

During the early post-natal period, offspring are vulnerable to environmental insults, such as
nutritional and hormonal changes, which increase risk to develop metabolic diseases later …

An interaction between obesity, impaired glucose metabolism and sperm function in adults
has been observed but it is not known whether exposure to a diet high in fat during the peri …

Sirtuins (SIRTs) are seven nicotinamide adenine dinucleotide (NAD+)-dependent protein
deacetylases enzymes (SIRT1–7) that play an important role in maintaining cellular …