Unraveling human brain development and evolution using organoid models
S Fernandes, D Klein, MC Marchetto - Frontiers in Cell and …, 2021 - frontiersin.org
Brain organoids are proving to be physiologically relevant models for studying human brain
development in terms of temporal transcriptional signature recapitulation, dynamic …
development in terms of temporal transcriptional signature recapitulation, dynamic …
Organ on a Chip: A Novel in vitro Biomimetic Strategy in Amyotrophic Lateral Sclerosis (ALS) Modeling
B Arjmand, S Kokabi Hamidpour, Z Rabbani… - Frontiers in …, 2022 - frontiersin.org
Amyotrophic lateral sclerosis is a pernicious neurodegenerative disorder that is associated
with the progressive degeneration of motor neurons, the disruption of impulse transmission …
with the progressive degeneration of motor neurons, the disruption of impulse transmission …
[HTML][HTML] Riluzole and novel naphthalenyl substituted aminothiazole derivatives prevent acute neural excitotoxic injury in a rat model of temporal lobe epilepsy
T Kyllo, V Singh, H Shim, S Latika, HM Nguyen… - …, 2023 - Elsevier
Epileptogenic seizures, or status epilepticus (SE), leads to excitotoxic injury in hippocampal
and limbic neurons in the kainic acid (KA) animal model of temporal lobe epilepsy (TLE) …
and limbic neurons in the kainic acid (KA) animal model of temporal lobe epilepsy (TLE) …
[HTML][HTML] Ozone pollution, oxidative stress, synaptic plasticity, and neurodegeneration
PC Bello-Medina, E Rodríguez-Martínez… - Neurología (English …, 2022 - Elsevier
Introduction Overpopulation and industrial growth result in an increase in air pollution,
mainly due to suspended particulate matter and the formation of ozone. Repeated exposure …
mainly due to suspended particulate matter and the formation of ozone. Repeated exposure …
UNC13A variant rs12608932 is associated with increased risk of amyotrophic lateral sclerosis and reduced patient survival: a meta-analysis
B Yang, H Jiang, F Wang, S Li, C Wu, J Bao, Y Zhu… - Neurological …, 2019 - Springer
Background Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease associated
with both genetic and environmental risk factors. Previous studies trying to find an …
with both genetic and environmental risk factors. Previous studies trying to find an …
Respiratory management of patients with neuromuscular disease: current perspectives
G Pfeffer, M Povitz - Degenerative Neurological and …, 2016 - Taylor & Francis
Neuromuscular ventilatory weakness can be difficult to recognize because the symptoms
can be nocturnal, nonspecific, or attributed to other conditions. The presence of respiratory …
can be nocturnal, nonspecific, or attributed to other conditions. The presence of respiratory …
An overview of mitochondrial protein defects in neuromuscular diseases
F Marra, P Lunetti, R Curcio, FM Lasorsa… - Biomolecules, 2021 - mdpi.com
Neuromuscular diseases (NMDs) are dysfunctions that involve skeletal muscle and cause
incorrect communication between the nerves and muscles. The specific causes of NMDs are …
incorrect communication between the nerves and muscles. The specific causes of NMDs are …
Evidence for dying‐back axonal degeneration in age‐associated skeletal muscle decline
Introduction Age‐associated muscle strength decline is a major contributing factor to
increased late‐life functional decline and comorbidity, and is strongly associated with early …
increased late‐life functional decline and comorbidity, and is strongly associated with early …
TDP-43 and limbic-predominant age-related TDP-43 encephalopathy
L Zhang, Y Chen, M Liu, Y Wang… - Frontiers in aging …, 2020 - frontiersin.org
Through a number of an extensive autopsy, biomarker, and genomics studies, researchers
have recently defined a novel type of dementia known as limbic-predominant age-related …
have recently defined a novel type of dementia known as limbic-predominant age-related …
CACNA1H missense mutations associated with amyotrophic lateral sclerosis alter Cav3.2 T-type calcium channel activity and reticular thalamic neuron firing
Y Rzhepetskyy, J Lazniewska, I Blesneac, R Pamphlett… - Channels, 2016 - Taylor & Francis
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects
nerve cells in the brain and the spinal cord. In a recent study by Steinberg and colleagues, 2 …
nerve cells in the brain and the spinal cord. In a recent study by Steinberg and colleagues, 2 …