Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine expressed by different
cell types and exerting multiple biological functions. It has been shown that MIF may be …

Purpose Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder
with on average a 1-year delay between symptom onset and diagnosis. Studies have …

Neurodegenerative diseases are characterized by progressive neuronal loss anatomically
or physiologically and accumulation of protein in the cells. Mitochondria provide energy to …

Background Epidemiological studies highlighted the possibility that exposure to cyanotoxins
leads to the development of the neurodegenerative disease amyotrophic lateral sclerosis …

Aims Amyotrophic lateral sclerosis (ALS) is characterized by degeneration of motoneurons
and progressive muscle wasting. Inflammatory processes, mediated by non‐neuronal cells …

Background Respiratory failure represents an unavoidable step in patients with amyotrophic
lateral sclerosis (ALS) and other motor neuron diseases (MND). The development of …

Objectives: Despite distinct clinical profiles, amyotrophic lateral sclerosis (ALS) and
frontotemporal dementia (FTD) patients share a remarkable portion of pathological features …

Many lines of evidence have highlighted the role played by heterogeneous nuclear
ribonucleoproteins in amyotrophic lateral sclerosis. In this study, we have aimed to identify …

Background The large-scale survey about amyotrophic lateral sclerosis (ALS) based on both
population and hospitals in the Chinese mainland has been deficient at present. To this end …

To define the presence and type of frontotemporal dysfunction in amyotrophic lateral
sclerosis (ALS), different screening tools have been created. Currently, the most used …