Acute generalized weakness

L Ganti, V Rastogi - Neurologic Emergencies: How to Do a Fast, Focused …, 2018 - Springer
A 37-year-old male presents to your emergency department Saturday afternoon complaining
of generalized weakness, a feeling of being wiped out, and no strength in his legs. It started …

Standardized reporter systems for purification and imaging of human pluripotent stem cell-derived motor neurons and other cholinergic cells

A Garcia-Diaz, G Efe, K Kabra, A Patel, ER Lowry… - Neuroscience, 2020 - Elsevier
Reliable and consistent pluripotent stem cell reporter systems for efficient purification and
visualization of motor neurons are essential reagents for the study of normal motor neuron …

Evaluating person-centered factors associated with brain–computer interface access to a commercial augmentative and alternative communication paradigm

KM Pitt, JS Brumberg - Assistive Technology, 2022 - Taylor & Francis
Current BCI-AAC systems largely utilize custom-made software and displays that may be
unfamiliar to AAC stakeholders. Further, there is limited information available exploring the …

Papez circuit gray matter and episodic memory in amyotrophic lateral sclerosis and behavioural variant frontotemporal dementia

APA Bueno, LC de Souza, WHL Pinaya… - Brain Imaging and …, 2021 - Springer
Amyotrophic lateral sclerosis and behavioural variant frontotemporal dementia are two
different diseases recognized to overlap at clinical, pathological and genetic characteristics …

BMP/TGF‐β signaling as a modulator of neurodegeneration in ALS

K Russo, KA Wharton - Developmental Dynamics, 2022 - Wiley Online Library
This commentary focuses on the emerging intersection between BMP/TGF‐β signaling roles
in nervous system function and the amyotrophic lateral sclerosis (ALS) disease state. Future …

Characterization of the amyotrophic lateral sclerosis-linked P56S mutation of the VAPB gene in Southern Brazil

MLC Trilico, PJ Lorenzoni, CSK Kay… - … Lateral Sclerosis and …, 2020 - Taylor & Francis
Objective: Amyotrophic lateral sclerosis (ALS) is a rare worldwide heterogeneous
neurodegenerative disease with sporadic and familial (FALS) forms. A rare autosomal …

[HTML][HTML] Phosphoinositide-3-kinase regulatory subunit 4 participates in the occurrence and development of amyotrophic lateral sclerosis by regulating autophagy

Y Liu, CH Wei, C Li, WZ Chen, Y Zhu… - Neural Regeneration …, 2022 - journals.lww.com
The development of amyotrophic lateral sclerosis (ALS) may be related to the abnormal
alterations of multiple proteins. Our previous study revealed that the expression of …

Motor neuron disease mortality rates in US states are associated with well water use

GG Schwartz, MG Klug - Amyotrophic Lateral Sclerosis and …, 2016 - Taylor & Francis
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with an unknown cause
and invariably fatal outcome. We sought to evaluate a correlation between motor neuron …

Flexibility of fast brain dynamics and disease severity in amyotrophic lateral sclerosis

A Polverino, E Troisi Lopez, R Minino, M Liparoti… - Neurology, 2022 - AAN Enterprises
Background and Objectives Amyotrophic lateral sclerosis (ALS) is a multisystem disorder, as
supported by clinical, molecular, and neuroimaging evidence. As a consequence, predicting …

Anterior insula is more vulnerable than posterior insula to TDP-43 pathology in common dementias and ALS

RH Lochner, AS Arumanayagam… - … of Neuropathology & …, 2024 - academic.oup.com
Based on the anatomic proximity, connectivity, and functional similarities between the
anterior insula and amygdala, we tested the hypothesis that the anterior insula is an …