Methods To test this hypothesis, we quantified flexibility utilizing the “functional repertoire”(ie
the number of configurations of active brain areas) as measured from source-reconstructed …

Increased accumulation of transcribed protein from damaged DNA and the decreased ability
to repair DNA lead to many neurodegenerative diseases that lack effective therapies. Gene …

ABSTRACT The Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease that
affects motor neuron and decreases muscle functionality. As it is a cumulative disease, it will …

Brain computer interfaces based on sensorimotor rhythms modulation (SMR-BCIs) allow
people to emit commands to an interface by imagining right hand, left hand or feet …

In this final chapter, we highlight some of the key chapter topics in this book and provide an
overview of disease etiology, mechanisms, and progression of amyotrophic lateral sclerosis …

INTRODUCCIÓN: La Esclerosis Lateral Amiotrófica (ELA) es una enfermedad del sistema
nervioso central caracterizada por una degeneración progresiva de las neuronas motoras …

Aims: Amyotrophic lateral sclerosis (ALS) is characterized by degeneration of motoneurons
and progressive muscle wasting. Inflammatory processes, mediated by non-neuronal cells …

Hexanucleotide repeat expansions in the C9orf72 gene is the prevalent genetic cause of
ALS, causing neurodegeneration through two gain-of-function mechanisms due to the …

The Hippo pathway is a cell signaling pathway involved in organ size regulation and
tumorigenesis in mammals. This pathway regulates the activity of Yes-associated protein …

Abstract A Esclerose Lateral Amiotrófica (ELA) é uma doença neurodegenerativa que afeta
os neurônios motores do córtex, tronco encefálico e medula espinhal. Dentre as hipóteses …