[HTML][HTML] Combination of multiple omics techniques for a personalized therapy or treatment selection

C Massa, B Seliger - Frontiers in Immunology, 2023 - frontiersin.org
Despite targeted therapies and immunotherapies have revolutionized the treatment of
cancer patients, only a limited number of patients have long-term responses. Moreover, due …

Aldose reductase and cancer metabolism: The master regulator in the limelight

NP Syamprasad, S Jain, B Rajdev, N Prasad… - Biochemical …, 2023 - Elsevier
It is strongly established that metabolic reprogramming mediates the initiation, progression,
and metastasis of a variety of cancers. However, there is no common biomarker identified to …

NUPR1 imparts oncogenic potential in bladder cancer

L Zhang, S Gao, X Shi, Y Chen, S Wei, Y Mi… - Cancer …, 2023 - Wiley Online Library
Abstract Background NUPR1, or p8, is a small chromatin protein that plays a central role in
the resistance to treatment and progression of cancer. Nevertheless, the molecular …

[HTML][HTML] Telomere-related prognostic biomarkers for survival assessments in pancreatic cancer

S Chen, S Hu, B Zhou, B Cheng, H Tong, D Su, X Li… - Scientific Reports, 2023 - nature.com
Human telomeres are linked to genetic instability and a higher risk of developing cancer.
Therefore, to improve the dismal prognosis of pancreatic cancer patients, a thorough …

[HTML][HTML] A novel lipid metabolism-based risk model associated with immunosuppressive mechanisms in diffuse large B-cell lymphoma

Z Zhang, C Zhao, S Yang, W Lu, J Shi - Lipids in Health and Disease, 2024 - Springer
Background The molecular diversity exhibited by diffuse large B-cell lymphoma (DLBCL) is
a significant obstacle facing current precision therapies. However, scoring using the …

Weighted gene co‐expression network analysis and machine learning identified the lipid metabolism‐related gene LGMN as a novel biomarker for keloid

Q Wang, X Huang, S Zeng, R Zhou… - Experimental …, 2024 - Wiley Online Library
The aetiology of keloid formation remains unclear, and existing treatment modalities have
not definitively established a successful approach. Therefore, it is necessary to identify …

[HTML][HTML] Combined analysis of bulk and single-cell RNA sequencing reveals novel natural killer cell-related prognostic biomarkers for predicting immunotherapeutic …

K Zhang, E Yuan - Frontiers in Immunology, 2023 - frontiersin.org
Introduction Natural killer (NK) cells play an irreplaceable and important role as a subtype of
innate immune cells in the contemporary setting of antitumor immunity. Methods We chose a …

[HTML][HTML] Exosome and lipid metabolism-related genes in pancreatic adenocarcinoma: a prognosis analysis

J Wu, Y Li, G Nabi, X Huang, X Zhang, Y Wang… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Objective: The purpose of the study was to investigate the role of exosome and lipid
metabolism-related genes (EALMRGs) mRNA levels in the diagnosis and prognosis of …

[HTML][HTML] A novel stemness-hypoxia-related signature for prognostic stratification and immunotherapy response in hepatocellular carcinoma

G Zhang, K Zhang, Y Zhao, Q Yang, X Lv - BMC cancer, 2022 - Springer
Background The specific differentiation potential, unlimited proliferation, and self-renewal
capacity of cancer stem cells (CSCs) are closely related to the occurrence, recurrence, and …

Establishment of a risk score model for bladder urothelial carcinoma based on energy metabolism‐related genes and their relationships with immune infiltration

C Huang, Y Li, Q Ling, C Wei, B Fang, X Mao… - FEBS Open …, 2023 - Wiley Online Library
Bladder urothelial carcinoma (BLCA) is a common malignant tumor of the human urinary
system, and a large proportion of BLCA patients have a poor prognosis. Therefore, there is …