The present review contains data from literature concerning the in vivo structure of synovial
membranes in healthy people and patients with rheumatoid arthritis (RA). The properties of …

Microarray and deep sequencing technologies have provided unprecedented opportunities
for mapping genome mutations, RNA transcripts, transcription factor binding, and histone …

The modification of proteins by small ubiquitin-related modifier (SUMO) molecules,
SUMOylation, is a key post-translational modification involved in a variety of biological …

Alterations in DNA methylation patterns have been related to several diseases, including
Rheumatoid Arthritis (RA). CD4+ T-cells are critical players for the early pathogenesis of RA …

La epigenética, como ciencia que estudia la modificaciones heredables en la función del
genoma que se realizan sin cambios en la secuencia del ADN, está atrayendo una atención …

There is growing evidence that implicates the epigenome in the development of bone and
joint disorders. The complexity and dynamic nature of epigenetic regulations confound the …

Romatoid artrit batı toplumlarında% 1 sıklıkla görülen otoimmün inflamatuar bir hastalıktır.
Primer olarak diartrodial eklemleri tutan, spontan remisyonlarla seyreden simetrik sinovitten …

Inflammatory arthritides include a group of joint disorders characterized by joint pain,
swelling, warmth and stiffness. They are associated with synovitis and synovial hyperplasia …

Autoimmune disorders are a set of diseases where the immune system losses self-tolerance
to self-antigens and attacks self-tissues, leading to organ damages. The pathogenesis of …

Publisher Summary This chapter discusses the role of epigenetics in immune disorders. The
immune system enables the organism to resist infections and is composed of the innate or …