Abstract Interleukin-22 (IL-22) plays an important role in the treatment of organ failure, which
can induce anti-apoptotic and proliferative signaling pathways; Nevertheless, the practical …

Metabolic disorders are currently threatening public health worldwide. Discovering new
targets and developing promising drugs will reduce the global metabolic-related disease …

In recent years, there have been important advances in our understanding of alcohol-
associated hepatitis (AH), which have occurred in parallel with a surge in clinical trial …

Alcohol-related liver disease (ALD) became an important health issue worldwide. Following
chronic alcohol consumption, the development of ALD might be caused by metabolic and …

This review explores the biological aspects of neutrophils, their contributions to the
development of steatotic liver disease, and their potential as therapeutic targets for the …

Alcohol-associated liver disease (ALD) has been recognized as the most common cause of
advanced liver disease worldwide, though mechanisms of pathogenesis remain …

Research Priorities and Future Landscape of Clinical Trials in Alcohol-Associated Liver
Disease - Clinics in Liver Disease Skip to Main Content Skip to Main Menu Advertisement …

Abstract Melanoma differentiation-associated gene-7 (MDA-7)/interleukin-24 (IL-24) is a
pleiotropic member of the IL-10 family of cytokines, and is involved in multiple biological …

METHODS: All patients admitted for severe AH between 2002 and 2020 were prospectively
included. Systematic screening for infection was performed at admission and renewed in the …

Xiang et al. published interesting insights about the role of interleukin (IL)-22 in acute-on-
chronic liver failure (ACLF). 1 The authors elegantly analysed the effects of IL-22 in a mouse …