Fetal origins of insulin resistance and the metabolic syndrome: a key role for adipose tissue?
T Meas - Diabetes & metabolism, 2010 - Elsevier
For several years now, the epidemiological data have shown an inverse relationship
between birth-weight and the development in later life of cardiovascular disease and …
between birth-weight and the development in later life of cardiovascular disease and …
[HTML][HTML] Neonatal overfeeding alters adult anxiety and stress responsiveness
SJ Spencer, A Tilbrook - Psychoneuroendocrinology, 2009 - Elsevier
The neonatal nutritional environment is critical for programming the systems regulating body
weight, and an inappropriate nutritional environment in early life can lead to overweight or …
weight, and an inappropriate nutritional environment in early life can lead to overweight or …
Evolution of obesity in a low birth weight cohort
PH Casey, RH Bradley, L Whiteside-Mansell… - Journal of …, 2012 - nature.com
Objective: The objective of this study was to determine the evolution of obesity status (OS) in
a longitudinal cohort of low birth weight preterm (LBWPT) infants to an age of 8 years, and to …
a longitudinal cohort of low birth weight preterm (LBWPT) infants to an age of 8 years, and to …
Weight gain in childhood and body composition at 18 years of age in Brazilian males
Aim: To assess the association between weight gain at different time periods during
childhood and measures of adiposity in late adolescence. Methods: A population‐based …
childhood and measures of adiposity in late adolescence. Methods: A population‐based …
[HTML][HTML] Ancient origins of low lean mass among South Asians and implications for modern type 2 diabetes susceptibility
Abstract Living South Asians have low lean tissue mass relative to height, which contributes
to their elevated type 2 diabetes susceptibility, particularly when accompanied by obesity …
to their elevated type 2 diabetes susceptibility, particularly when accompanied by obesity …
Maternal pre-pregnancy BMI, gestational weight gain, and age at menarche in daughters
J Deardorff, R Berry-Millett, D Rehkopf… - Maternal and child …, 2013 - Springer
Life course theory suggests that early life experiences can shape health over a lifetime and
across generations. Associations between maternal pregnancy experience and daughters' …
across generations. Associations between maternal pregnancy experience and daughters' …
Postnatal β2 adrenergic treatment improves insulin sensitivity in lambs with IUGR but not persistent defects in pancreatic islets or skeletal muscle
DT Yates, LE Camacho, AC Kelly… - The Journal of …, 2019 - Wiley Online Library
Key points Previous studies in fetuses with intrauterine growth restriction (IUGR) have
shown that adrenergic dysregulation was associated with low insulin concentrations and …
shown that adrenergic dysregulation was associated with low insulin concentrations and …
Intrauterine growth-restricted sheep fetuses exhibit smaller hindlimb muscle fibers and lower proportions of insulin-sensitive Type I fibers near term
DT Yates, CN Cadaret, KA Beede… - American Journal …, 2016 - journals.physiology.org
Intrauterine growth restriction (IUGR) reduces muscle mass and insulin sensitivity in
offspring. Insulin sensitivity varies among muscle fiber types, with Type I fibers being most …
offspring. Insulin sensitivity varies among muscle fiber types, with Type I fibers being most …
The influence of leptin on early life programming of obesity
CJ Stocker, MA Cawthorne - Trends in biotechnology, 2008 - cell.com
Epidemiological evidence together with experimental models shows a direct relationship
between fetal and early postnatal growth patterns and an increased risk of adult metabolic …
between fetal and early postnatal growth patterns and an increased risk of adult metabolic …
[HTML][HTML] Corticotropin-releasing hormone as the homeostatic rheostat of feto-maternal symbiosis and developmental programming in utero and neonatal life
V Alcántara-Alonso, P Panetta, P De Gortari… - Frontiers in …, 2017 - frontiersin.org
A balanced interaction between the homeostatic mechanisms of mother and the developing
organism during pregnancy and in early neonatal life is essential in order to ensure optimal …
organism during pregnancy and in early neonatal life is essential in order to ensure optimal …