This review summarizes the current understanding of the role of plasma membrane
transporters in regulating intracellular inorganic phosphate ([Pi] In) in mammals. Pi influx is …

In addition to their standard inorganic phosphate (Pi) nutritional function, Pi transporters
have additional roles in several cells, including Pi sensing (the so-called transceptor) and a …

Phosphorus, an essential nutrient, performs vital functions in skeletal and non-skeletal
tissues and is pivotal for energy production. The last two decades of research on the …

Inorganic phosphate (Pi) is an essential nutrient for living organisms and is maintained in
equilibrium in the range of 0.8–1.4 mM Pi. Pi is a source of organic constituents for DNA …

Tumor cells develop a high demand for inorganic phosphate (Pi) due to their high growth
rates and energy requirements. Serum Pi concentrations in cancer patients have been found …

Introduction Temporomandibular joint (TMJ) osteoarthritis (OA) is a common TMJ
degenerative disease with an unclear mechanism. Synovial fluid (SF), an important …

Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is an important
adverse event in the development of chronic obstructive pulmonary disease (COPD) …

Phosphate ions are the most abundant anions inside the cells, and they are increasingly
gaining attention as key modulators of cellular function and gene expression. However, little …

Phosphorus is one of the essential mineral elements of animals that plays an important role
in animal growth and development, bone formation, energy metabolism, nucleic acid …

For cells to obtain inorganic phosphate, ectoenzymes in the plasma membrane, which
contain a catalytic site facing the extracellular environment, hydrolyze phosphorylated …