[HTML][HTML] Radioiodine therapy in advanced differentiated thyroid cancer: Resistance and overcoming strategy

Y Liu, J Wang, X Hu, Z Pan, T Xu, J Xu, L Jiang… - Drug Resistance …, 2023 - Elsevier
Thyroid cancer is the most prevalent endocrine tumor and its incidence is fast-growing
worldwide in recent years. Differentiated thyroid cancer (DTC) is the most common …

Could oxidative stress play a role in the development and clinical management of differentiated thyroid cancer?

M Kościuszko, A Buczyńska, AJ Krętowski… - Cancers, 2023 - mdpi.com
Simple Summary Increased oxidative stress (OS) has been implicated as a relevant risk
factor for cancer development and progression. The incidence of differentiated thyroid …

Anlotinib in locally advanced or metastatic medullary thyroid carcinoma: a randomized, double-blind phase IIB trial

D Li, Y Chi, X Chen, M Ge, Y Zhang, Z Guo… - Clinical Cancer …, 2021 - AACR
Purpose: Medullary thyroid cancer (MTC) accounts for about 2% of all thyroid cancer, but
has a relatively poor prognosis compared with differentiated thyroid cancer. Anlotinib is a …

The efficacy and safety of anlotinib in neoadjuvant treatment of locally advanced thyroid cancer: a single-arm phase II clinical trial

N Huang, W Wei, J Xiang, J Chen, Q Guan, Z Lu, B Ma… - Thyroid, 2021 - liebertpub.com
Background: Surgery is the primary treatment for locally advanced thyroid cancer. For some
cases, R0/R1 resection could not be achieved at initial diagnosis and neoadjuvant treatment …

Shared hotspot mutations in oncogenes position dogs as an unparalleled comparative model for precision therapeutics

L Rodrigues, J Watson, Y Feng, B Lewis, G Harvey… - Scientific Reports, 2023 - nature.com
Naturally occurring canine cancers have remarkable similarities to their human counterparts.
To better understand these similarities, we investigated 671 client-owned dogs from 96 …

[HTML][HTML] Molecular basis and targeted therapy in thyroid cancer: progress and opportunities

L Zhang, Q Feng, J Wang, Z Tan, Q Li, M Ge - Biochimica et Biophysica …, 2023 - Elsevier
Thyroid cancer (TC) is the most prevalent endocrine malignant tumor. Surgery,
chemotherapy, radiotherapy, and radioactive iodine (RAI) therapy are the standard TC …

Efficacy and safety of selpercatinib in Chinese patients with advanced RET-altered thyroid cancers: results from the phase II LIBRETTO-321 study

X Zheng, Q Ji, Y Sun, M Ge, B Zhang… - Therapeutic …, 2022 - journals.sagepub.com
Background: Selpercatinib, a highly selective and potent REarranged during Transfection
(RET) kinase inhibitor, is effective in advanced RET-altered thyroid cancer (TC). However …

Ferroptosis inducers in thyroid cancer

KR Sekhar, S Cyr, N Baregamian - World Journal of Surgery, 2023 - Springer
Purpose Papillary thyroid carcinoma (PTC) progression imparts reduced patient survival.
Tumor resistance and progression can be influenced by Glutathione (GSH) metabolism …

[HTML][HTML] Bibliometric insights in advances of anaplastic thyroid cancer: research landscapes, turning points, and global trends

H Wang, Y Yu, K Wang, H Sun - Frontiers in Oncology, 2021 - frontiersin.org
Background Thyroid cancers are the most common endocrine malignancies with a dramatic
increase in incidences. Anaplastic thyroid cancer is a rare but deadly form among thyroid …

Thyroid Carcinoma with NSD3::NUTM1 Fusion: a Case with Thyrocyte Differentiation and Colloid Production

DB Allison, J Rueckert, V Cornea, CY Lee, J Dueber… - Endocrine …, 2022 - Springer
In this report, we present a high-grade thyroid carcinoma with an NSD3:: NUTM1 fusion
detected on expanded next-generation sequencing testing. Nuclear protein of the testis …