Tuberculous meningitis

RJ Wilkinson, U Rohlwink, UK Misra… - Nature reviews …, 2017 - nature.com
Tuberculosis remains a global health problem, with an estimated 10.4 million cases and 1.8
million deaths resulting from the disease in 2015. The most lethal and disabling form of …

Tuberculous meningitis: progress and remaining questions

J Huynh, J Donovan, NH Phu, HDT Nghia… - The Lancet …, 2022 - thelancet.com
Tuberculous meningitis is a devastating brain infection that is caused by Mycobacterium
tuberculosis and is notoriously difficult to diagnose and treat. New technologies …

[图书][B] Osborn's brain e-book

AG Osborn, GL Hedlund, KL Salzman - 2017 - books.google.com
Comprehensive, visually appealing, and easy to understand, Osborn's Brain, second
edition, by the highly esteemed Dr. Anne G. Osborn, provides a solid framework for …

The pathogenesis of tuberculous meningitis

AG Davis, UK Rohlwink, A Proust… - Journal of leukocyte …, 2019 - academic.oup.com
Tuberculosis (TB) remains a leading cause of death globally. Dissemination of TB to the
brain results in the most severe form of extrapulmonary TB, tuberculous meningitis (TBM) …

The Immune Response to Mycobacterium tuberculosis in HIV-1-Coinfected Persons

H Esmail, C Riou, E du Bruyn, RPJ Lai… - Annual review of …, 2018 - annualreviews.org
Globally, about 36.7 million people were living with HIV infection at the end of 2015. The
most frequent infection co-occurring with HIV-1 is Mycobacterium tuberculosis—374,000 …

Role of neutrophils in tuberculosis: a bird's eye view

JN Hilda, S Das, SP Tripathy, LE Hanna - Innate immunity, 2020 - journals.sagepub.com
Neutrophils are innate immune cells implicated in the process of killing Mycobacterium
tuberculosis early during infection. Once the mycobacteria enter the human system …

[HTML][HTML] Treatment of tuberculous meningitis and its complications in adults

A Davis, G Meintjes, RJ Wilkinson - Current treatment options in neurology, 2018 - Springer
Purpose of review Tuberculous meningitis (TBM) is a global health problem. In this review,
we systematically evaluate the evidence for current and emerging antimicrobials, host …

[HTML][HTML] Tuberculosis IRIS: pathogenesis, presentation, and management across the spectrum of disease

CM Quinn, V Poplin, J Kasibante, K Yuquimpo… - Life, 2020 - mdpi.com
Antiretroviral therapy (ART), while essential in combatting tuberculosis (TB) and HIV
coinfection, is often complicated by the TB-associated immune reconstitution inflammatory …

[HTML][HTML] Lysosomal Cathepsin Release Is Required for NLRP3-Inflammasome Activation by Mycobacterium tuberculosis in Infected Macrophages

EP Amaral, N Riteau, M Moayeri, N Maier… - Frontiers in …, 2018 - frontiersin.org
Lysosomal cathepsin B (CTSB) has been proposed to play a role in the induction of acute
inflammation. We hypothesised that the presence of active CTSB in the cytosol is crucial for …

[HTML][HTML] The tuberculosis-associated immune reconstitution inflammatory syndrome: recent advances in clinical and pathogenesis research

NF Walker, C Stek, S Wasserman… - Current Opinion in …, 2018 - journals.lww.com
Specific biomarkers would aid in identifying high-risk patients for interventions and a
diagnostic test is needed. Clinicians should consider prednisone for TB-IRIS prevention in …