Ca2+ plays a crucial role in connecting membrane excitability with contraction in
myocardium. The hallmark features of heart failure are mechanical dysfunction and …

Erectile dysfunction is defined as the inability to achieve and maintain an erection sufficient
to permit satisfactory sexual intercourse. 1 It has been estimated to affect 20 million to 30 …

1–«МНОЦ МГУ им. МВ Ломоносова», 119192, Москва, Ломоносовский пр-кт, д. 27, корп.
10 2–ФГБОУ ВО «ПИМУ» МЗ РФ, 603950, Нижний Новгород, пл. Минина и Пожарского …

РЕКОМЕНДАЦИИ, СЕРДЕЧНАЯ НЕДОСТАТОЧНОСТЬ, ХРОНИЧЕСКАЯ СЕРДЕЧНАЯ
НЕДОСТАТОЧНОСТЬ, ОСТРАЯ ДЕКОМПЕНСАЦИЯ СЕРДЕЧНОЙ …

In less than 20 years, the first selective type 5 phosphodiesterase inhibitor, sildenafil, has
evolved from a potential anti-angina drug to an on-demand oral treatment for erectile …

Introduction Treatment of erectile dysfunction is based on pharmacotherapy for most
patients. Aim To review the current data on pharmacotherapy for erectile dysfunction based …

Sexual activity is an important component of patient and partner quality of life for men and
women with cardiovascular disease (CVD), including many elderly patients. 1 Decreased …

Background—In heart failure (HF), a defective nitric oxide signaling is involved in left
ventricular (LV) diastolic abnormalities and remodeling. PDE5 inhibition, by blocking …

Background—Sildenafil was recently approved for the treatment of pulmonary arterial
hypertension. The beneficial effects of phosphodiesterase type 5 (PDE5) inhibitors in …

A significant proportion of men with erectile dysfunction (ED) exhibit early signs of coronary
artery disease (CAD), and this group may develop more severe CAD than men without ED …