Optical coherence tomography (angiography) biomarkers in the assessment and monitoring of diabetic macular edema

CI Suciu, VI Suciu, SD Nicoara - Journal of Diabetes Research, 2020 - Wiley Online Library
Retinopathy is one of the most severe diabetes‐related complications, and macular edema
is the major cause of central vision loss in patients with diabetes mellitus. Significant …

[HTML][HTML] A review of traditional Chinese medicine on treatment of diabetic retinopathy and involved mechanisms

X Ai, P Yu, Y Hou, X Song, J Luo, N Li, X Lai… - Biomedicine & …, 2020 - Elsevier
As a common ocular complication and microangiopathy of type 2 diabetic mellitus, diabetic
retinopathy (DR) can lead to vision loss or even blindness in diabetic patients. At present …

Sequential restoration of external limiting membrane and ellipsoid zone after intravitreal anti-VEGF therapy in diabetic macular oedema

S De, S Saxena, A Kaur, AA Mahdi, A Misra, M Singh… - Eye, 2021 - nature.com
Abstract Background/Objectives To study the mechanism of restoration of retinal
photoreceptor ellipsoid zone (EZ), after intravitreal bevacizumab (IVB) therapy, in diabetic …

Ellipsoid zone integrity and visual acuity changes during diabetic macular edema therapy: a longitudinal study

LJ Kessler, GU Auffarth, D Bagautdinov… - Journal of Diabetes …, 2021 - Wiley Online Library
Purpose. Ellipsoid zone (EZ) integrity is identified as a potential biomarker for therapy
surveillance and outcome prediction of visual acuity (VA). However, only a few studies report …

[HTML][HTML] Deep Learning Algorithm Detects Presence of Disorganization of Retinal Inner Layers (DRIL)–An Early Imaging Biomarker in Diabetic Retinopathy

R Singh, S Singuri, J Batoki, K Lin, S Luo… - … Vision Science & …, 2023 - jov.arvojournals.org
Purpose: To develop and train a deep learning-based algorithm for detecting
disorganization of retinal inner layers (DRIL) on optical coherence tomography (OCT) to …

[HTML][HTML] A new approach to staging diabetic eye disease: staging of diabetic retinal neurodegeneration and diabetic macular edema

R Channa, RM Wolf, R Simo, M Brigell, P Fort… - Ophthalmology …, 2023 - Elsevier
Topic The goal of this review was to summarize the current level of evidence on biomarkers
to quantify diabetic retinal neurodegeneration (DRN) and diabetic macular edema (DME) …

Indicators of visual prognosis in diabetic macular oedema

S Sen, K Ramasamy, S Sivaprasad - Journal of Personalized Medicine, 2021 - mdpi.com
Diabetic macular oedema (DMO) is an important cause of moderate vision loss in people
with diabetes. Advances in imaging technology have shown that a significant proportion of …

Interleaved optical coherence tomography: Clinical and laboratory biomarkers in patients with diabetic macular edema

CI Suciu, VI Suciu, A Cuţaş, SD Nicoară - Journal of Personalized …, 2022 - mdpi.com
(1) Background: The global burden of diabetes mellitus (DM) has been estimated to reach
600 million patients worldwide by 2040. Approximately 200 million people will develop …

Diabetic retinopathy: soluble and imaging ocular biomarkers

M Ferrara, A Loda, G Coco, P Grassi, S Cestaro… - Journal of Clinical …, 2023 - mdpi.com
Diabetic retinopathy (DR), the most common microvascular complication of diabetes
mellitus, represents the leading cause of acquired blindness in the working-age population …

Long-term visual outcomes and morphologic biomarkers of vision loss in eyes with diabetic macular edema treated with anti-VEGF therapy

E Borrelli, D Grosso, C Barresi, G Lari… - American Journal of …, 2022 - Elsevier
Purpose To analyze the morphological characteristics and long-term visual outcomes in
eyes with diabetic retinopathy (DR) and diabetic macular edema (DME) treated with anti …