Viral Components Trafficking with (in) Extracellular Vesicles

F Rey-Cadilhac, F Rachenne, D Missé, J Pompon - Viruses, 2023 - mdpi.com
The global public health burden exerted by viruses partially stems from viruses' ability to
subdue host cells into creating an environment that promotes their multiplication (ie, pro …

Extracellular Vesicles in Flaviviridae Pathogenesis: Their Roles in Viral Transmission, Immune Evasion, and Inflammation

A Latanova, V Karpov, E Starodubova - International Journal of Molecular …, 2024 - mdpi.com
The members of the Flaviviridae family are becoming an emerging threat for public health,
causing an increasing number of infections each year and requiring effective treatment. The …

Zika virus modulates mitochondrial dynamics, mitophagy, and mitochondria-derived vesicles to facilitate viral replication in trophoblast cells

JK Lee, OS Shin - Frontiers in immunology, 2023 - frontiersin.org
Zika virus (ZIKV) remains a global public health threat with the potential risk of a future
outbreak. Since viral infections are known to exploit mitochondria-mediated cellular …

Extracellular vesicles recovered from plasma of severe dengue patients induce CD4+ T cell suppression through PD-L1/PD-1 interaction

S Kumari, B Bandyopadhyay, A Singh, S Aggarwal… - Mbio, 2023 - Am Soc Microbiol
Extracellular vesicles (EVs) are small membrane vesicles secreted into biological fluids,
which play crucial roles in influencing the cellular function in different pathological …

Control of maternal Zika virus infection during pregnancy is associated with lower antibody titers in a macaque model

NP Krabbe, E Razo, HJ Abraham, RV Spanton… - Frontiers in …, 2023 - frontiersin.org
Introduction Zika virus (ZIKV) infection during pregnancy results in a spectrum of birth
defects and neurodevelopmental deficits in prenatally exposed infants, with no clear …

Subcapsular sinus macrophages maximize germinal center development in non-draining lymph nodes during blood-borne viral infection

CC Aguilar, A Kalia, ME Brisse, KA Dowd… - Science …, 2024 - science.org
Lymph node (LN) germinal centers (GCs) are critical sites for B cell activation and
differentiation. GCs develop after specialized CD169+ macrophages residing in LN sinuses …

Cholesterol-linoleic acid liposomes induced extracellular vesicles secretion from immortalized adipose-derived mesenchymal stem cells for in vitro cell migration

JW Chen, FF Liew, HW Tan, M Misran… - Artificial Cells …, 2023 - Taylor & Francis
Extracellular vesicles (EVs) are small vesicles that are naturally released by cells and play a
crucial role in cell-to-cell communication, tissue repair and regeneration. As naturally …

Exosome-mediated antigen delivery: unveiling novel strategies in viral infection control and vaccine design

D El Safadi, A Mokhtari, M Krejbich, A Lagrave… - Vaccines, 2024 - mdpi.com
Exosomes are small subtypes of extracellular vesicles (EVs) naturally released by different
types of cells into their environment. Their physiological roles appear to be multiple, yet …

Dr Jekyll and Mr Hyde: From Two Branches of Immune Response to Three Types of Interferon Response

B Brown - 2023 - preprints.org
Interferons were the original prototype cytokine system discovered during research of the 20
th century. As the name suggests these were originally considered to be synthesised and …

A Review Study of the Participation of Late Domains in Sorting and Transport of Viral Factors to Exosomes

MA Velázquez-Cervantes, YR Benítez-Zeferino… - Life, 2023 - mdpi.com
Cellular communication depends heavily on the participation of vesicular systems generated
by most cells of an organism. Exosomes play central roles in this process. Today, these …