A brief review of cardiovascular diseases, associated risk factors and current treatment regimes
Cardiovascular diseases (CVDs) are the leading cause of premature death and disability in
humans and their incidence is on the rise globally. Given their substantial contribution …
humans and their incidence is on the rise globally. Given their substantial contribution …
[HTML][HTML] Is acetylsalicylic acid a safe and potentially useful choice for adult patients with COVID-19?
Abstract Severe Acute Respiratory Syndrome–Coronavirus-2 is responsible for the current
pandemic that has led to more than 10 million confirmed cases of Coronavirus Disease-19 …
pandemic that has led to more than 10 million confirmed cases of Coronavirus Disease-19 …
A survey of the structures of US FDA approved combination drugs
Combination drugs are an important class of US FDA approved pharmaceuticals. These
drugs have been on a continuous growth trajectory since the first combination drugs were …
drugs have been on a continuous growth trajectory since the first combination drugs were …
Fibrin clot structure and function: a role in the pathophysiology of arterial and venous thromboembolic diseases
A Undas, RAS Ariëns - Arteriosclerosis, thrombosis, and vascular …, 2011 - Am Heart Assoc
The formation of fibrin clots that are relatively resistant to lysis represents the final step in
blood coagulation. We discuss the genetic and environmental regulators of fibrin structure in …
blood coagulation. We discuss the genetic and environmental regulators of fibrin structure in …
[HTML][HTML] Potential role for tissue factor in the pathogenesis of hypercoagulability associated with in COVID-19
M Bautista-Vargas, F Bonilla-Abadía… - Journal of thrombosis and …, 2020 - Springer
In December 2019, a new and highly contagious infectious disease emerged in Wuhan,
China. The etiologic agent was identified as a novel coronavirus, now known as Severe …
China. The etiologic agent was identified as a novel coronavirus, now known as Severe …
NSAIDs and cardiovascular diseases: role of reactive oxygen species
R Ghosh, A Alajbegovic… - Oxidative medicine and …, 2015 - Wiley Online Library
Nonsteroidal anti‐inflammatory drugs (NSAIDs) are the most commonly used drugs
worldwide. NSAIDs are used for a variety of conditions including pain, rheumatoid arthritis …
worldwide. NSAIDs are used for a variety of conditions including pain, rheumatoid arthritis …
[HTML][HTML] The effects of aspirin on the outcome of COVID-19: a systematic review and meta-analysis
Background Repurposing the use of aspirin to treat hospitalized patients with COVID-19 is a
sensible approach. However, several previous studies showed conflicting results. This meta …
sensible approach. However, several previous studies showed conflicting results. This meta …
[HTML][HTML] Current and novel antiplatelet therapies for the treatment of cardiovascular diseases
G Jourdi, M Lordkipanidze, A Philippe… - International journal of …, 2021 - mdpi.com
Over the last decades, antiplatelet agents, mainly aspirin and P2Y12 receptor antagonists,
have significantly reduced morbidity and mortality associated with arterial thrombosis. Their …
have significantly reduced morbidity and mortality associated with arterial thrombosis. Their …
Combination antiplatelet and oral anticoagulant therapy in patients with coronary and peripheral artery disease: Focus on the COMPASS trial
Antiplatelet therapy is the mainstay for the treatment of acute and chronic arterial disease
involving the coronary and peripheral beds. However, questions remain about optimal …
involving the coronary and peripheral beds. However, questions remain about optimal …
Preventing the development of severe COVID-19 by modifying immunothrombosis
Background COVID-19-associated acute respiratory distress syndrome (ARDS) is
associated with significant morbidity and high levels of mortality. This paper describes the …
associated with significant morbidity and high levels of mortality. This paper describes the …