Vaccines comprising innovative adjuvants are rapidly reaching advanced translational
stages, such as the authorized nanotechnology adjuvants in mRNA vaccines against COVID …

During the past decades, anticancer immunotherapy has evolved from a promising
therapeutic option to a robust clinical reality. Many immunotherapeutic regimens are now …

This work describes the nature and strength of the immune response induced by various Toll-
like receptor ligands and their ability to act as vaccine adjuvants. It reviews the various …

Cancer immunotherapy is a growing field. GM-CSF, a potent cytokine promoting the
differentiation of myeloid cells, can also be used as an immunostimulatory adjuvant to elicit …

Adoptive immunotherapy, or the infusion of lymphocytes, is a promising approach for the
treatment of cancer and certain chronic viral infections. The application of the principles of …

Regulatory T cell (Treg) therapy has the potential to induce transplantation tolerance so that
immunosuppression and associated morbidity can be minimized. Alloantigen-reactive Tregs …

Advances in basic immunology have led to an improved understanding of the interactions
between the immune system and tumours, generating renewed interest in approaches that …

Cancer therapies based on T cells have shown impressive clinical benefit. In particular,
immune checkpoint blockade therapies with anti-CTLA-4 and anti-PD-1/PD-L1 are causing …

Purpose: Exosomes deliver signals to target cells and could thus be exploited as an
innovative therapeutic tool. We investigated the ability of membrane TRAIL-armed …

Toll-like receptors (TLRs) have first been characterized for their capacity to detect conserved
microbial components like lipopolysaccharide (LPS) and double-stranded RNA, resulting in …