A narrative review of molecular mechanism and therapeutic effect of cannabidiol (CBD)

J Peng, M Fan, C An, F Ni, W Huang… - Basic & clinical …, 2022 - Wiley Online Library
Cannabidiol (CBD) is an abundant non‐psychoactive phytocannabinoid in cannabis
extracts which has high affinity on a series of receptors, including Type 1 cannabinoid …

[HTML][HTML] The endocannabinoid system: a potential target for the treatment of various diseases

H Lowe, N Toyang, B Steele, J Bryant… - International journal of …, 2021 - mdpi.com
The Endocannabinoid System (ECS) is primarily responsible for maintaining homeostasis, a
balance in internal environment (temperature, mood, and immune system) and energy input …

[HTML][HTML] A comprehensive review on the techniques for extraction of bioactive compounds from medicinal cannabis

HMS Al Ubeed, DJ Bhuyan, MA Alsherbiny, A Basu… - Molecules, 2022 - mdpi.com
Cannabis is well-known for its numerous therapeutic activities, as demonstrated in pre-
clinical and clinical studies primarily due to its bioactive compounds. The Cannabis industry …

Pharmacological effects of cannabidiol by transient receptor potential channels

L Etemad, G Karimi, MS Alavi, A Roohbakhsh - Life Sciences, 2022 - Elsevier
Cannabidiol (CBD), as a major phytocannabinoid of Cannabis sativa, has emerged as a
promising natural compound in the treatment of diseases. Its diverse pharmacological …

[HTML][HTML] Extracellular vesicles of cannabis with high CBD content induce anticancer signaling in human hepatocellular carcinoma

T Tajik, K Baghaei, VE Moghadam, N Farrokhi… - Biomedicine & …, 2022 - Elsevier
Plant-derived extracellular vesicles (EVs) have been the topic of interest in recent years due
to their proven therapeutic properties. Intact or manipulated plant EVs have shown …

[HTML][HTML] Natural products as chemo-radiation therapy sensitizers in cancers

S Nisar, T Masoodi, KS Prabhu, S Kuttikrishnan… - Biomedicine & …, 2022 - Elsevier
Cancer is a devastating disease and is the second leading cause of death worldwide.
Surgery, chemotherapy (CT), and/or radiation therapy (RT) are the treatment of choice for …

[HTML][HTML] Cannabidiol (CBD) in cancer management

K O'Brien - Cancers, 2022 - mdpi.com
Simple Summary Cannabidiol (CBD) is one of the main constituents of the plant Cannabis
sativa. Surveys suggest that medicinal cannabis is popular amongst people diagnosed with …

Perfluorooctane sulfonate‐induced apoptosis in kidney cells by triggering the NOX4/ROS/JNK axis and antagonism of cannabidiol

Y Du, T Xu, D Luo, Y Wang, H Yin… - Environmental …, 2023 - Wiley Online Library
Perfluorooctane sulfonate (PFOS) is one of the persistent organic pollutants (POPs), which
can cause severe nephrotoxicity in mammals. Cannabinol (CBD), a nonpsychoactive …

[HTML][HTML] Molecular mechanism of cannabinoids in cancer progression

C Pagano, G Navarra, L Coppola, M Bifulco… - International Journal of …, 2021 - mdpi.com
Cannabinoids are a family of heterogeneous compounds that mostly interact with receptors
eliciting several physiological effects both in the central and peripheral nervous systems and …

A nanoformulation for immunosuppression reversal and broad-spectrum self-amplifying antitumor ferroptosis-immunotherapy

Q Yang, T Liu, H Zheng, Z Zhou, Y Huang, H Jia, S Fu… - Biomaterials, 2023 - Elsevier
The efficacy of immunotherapy combined with other therapeutic modalities in the
management of cancer has been extensively studied. However, no effective strategy to …