[HTML][HTML] Organoids
Z Zhao, X Chen, AM Dowbaj, A Sljukic… - Nature Reviews …, 2022 - nature.com
Organoids are simple tissue-engineered cell-based in vitro models that recapitulate many
aspects of the complex structure and function of the corresponding in vivo tissue. They can …
aspects of the complex structure and function of the corresponding in vivo tissue. They can …
[HTML][HTML] Recent advances in targeted strategies for triple-negative breast cancer
S Zhu, Y Wu, B Song, M Yi, Y Yan, Q Mei… - Journal of Hematology & …, 2023 - Springer
Triple-negative breast cancer (TNBC), a highly aggressive subtype of breast cancer,
negatively expresses estrogen receptor, progesterone receptor, and the human epidermal …
negatively expresses estrogen receptor, progesterone receptor, and the human epidermal …
[HTML][HTML] Predictive biomarkers of response to neoadjuvant chemotherapy in breast cancer: current and future perspectives for precision medicine
F Derouane, C van Marcke, M Berlière, A Gerday… - Cancers, 2022 - mdpi.com
Simple Summary Despite the increased use of neoadjuvant chemotherapy in the early
setting of breast cancer, there is a clinical need for predictive markers of response in daily …
setting of breast cancer, there is a clinical need for predictive markers of response in daily …
[HTML][HTML] The role of organoids in cancer research
Z Fang, P Li, F Du, L Shang, L Li - Experimental Hematology & Oncology, 2023 - Springer
Organoids are established through in vitro 3D culture, and they can mimic the structure and
physiological functions of organs or tissues in vivo. Organoids have attracted much attention …
physiological functions of organs or tissues in vivo. Organoids have attracted much attention …
From digital control to digital twins in medicine: A brief review and future perspectives
R Eftimie, A Mavrodin, SPA Bordas - Advances in Applied Mechanics, 2023 - Elsevier
The last few decades have been dominated by the need for digital control of various
processes in biology and medicine. Advances in artificial intelligence (AI) over the last few …
processes in biology and medicine. Advances in artificial intelligence (AI) over the last few …
[HTML][HTML] Perspectives for 3D-bioprinting in modeling of tumor immune evasion
R Staros, A Michalak, K Rusinek, K Mucha, Z Pojda… - Cancers, 2022 - mdpi.com
Simple Summary The ability of cancer cells to evade the immunological response of the host
has been recognized as one of the hallmarks of cancer. Better understanding of this …
has been recognized as one of the hallmarks of cancer. Better understanding of this …
[HTML][HTML] Applications of microphysiological systems to disease models in the biopharmaceutical industry: opportunities and challenges
O Irrechukwu, R Yeager, R David, J Ekert… - ALTEX-Alternatives to …, 2023 - altex.org
Disease models enable researchers to investigate, test, and identify therapeutic targets that
would alter the patients' disease condition and improve quality of life. Advances in genetic …
would alter the patients' disease condition and improve quality of life. Advances in genetic …
Mechanics constitutive models for viscoelastic solid materials: Development and a critical review
Mathematical constitutive models are crucially important for the real viscoelastic solid
materials in academic investigation and engineering application. The viscoelastic solid …
materials in academic investigation and engineering application. The viscoelastic solid …
[HTML][HTML] Head and neck cancer patient-derived tumouroid cultures: Opportunities and challenges
BWMTJ Basnayake, P Leo, S Rao, S Vasani… - British Journal of …, 2023 - nature.com
Head and neck cancers (HNC) are the seventh most prevalent cancer type globally. Despite
their common categorisation, HNCs are a heterogeneous group of malignancies arising in …
their common categorisation, HNCs are a heterogeneous group of malignancies arising in …
Microfluidic Organoid Cultures Derived from Pancreatic Cancer Biopsies for Personalized Testing of Chemotherapy and Immunotherapy
D Choi, AM Gonzalez‐Suarez, MG Dumbrava… - Advanced …, 2024 - Wiley Online Library
Patient‐derived cancer organoids (PDOs) hold considerable promise for personalizing
therapy selection and improving patient outcomes. However, it is challenging to generate …
therapy selection and improving patient outcomes. However, it is challenging to generate …