Antimicrobial-resistant ESKAPE (E nterococcus faecium, S taphylococcus aureus, K
lebsiella pneumoniae, A cinetobacter baumannii, P seudomonas aeruginosa, and E …

Antibiotics changed medical practice by significantly decreasing the morbidity and mortality
associated with bacterial infection. However, infectious diseases remain the leading cause …

Antimicrobial resistance is one of the major problems in current practical medicine. The
spread of genes coding for resistance determinants among bacteria challenges the use of …

We report a case of resistance development toward cefiderocol in a patient with intra-
abdominal and bloodstream infections caused by carbapenemase-producing Enterobacter …

Cefiderocol is a new cephalosporin displaying against extensively resistant (XDR) Gram-
negative bacteria. We report our experience with cefiderocol-based combination therapies …

Biofilm is an advanced form of protection that allows bacterial cells to withstand adverse
environmental conditions. The complex structure of biofilm results from genetic‐related …

β-Lactam antibiotics are the most widely prescribed antibacterial drugs due to their low
toxicity and broad spectrum. Their action is counteracted by different resistance mechanisms …

Introduction The human defense against microorganisms dates back to the ancient
civilizations, with attempts to use substances from vegetal, animal, or inorganic origin to fight …

Antimicrobial resistance continues to increase globally and treatment of difficult-to-treat
(DTT) infections, mostly associated with carbapenem-resistant (CR) Pseudomonas …

Abstract 48 new drugs including 38 chemical entities (33 new chemical entities, 3 new
diagnostic agents, and 2 payloads of antibody drug conjugates) and 10 biologics were …