Transient receptor potential vanilloid subtype 1 (TRPV1), a member of the transient receptor
potential vanilloid (TRPV) channel family, is a nonselective cation channel that is widely …

Chronic pain treatment remains a sore challenge, and in our aging society, the number of
patients reporting inadequate pain relief continues to grow. Current treatment options all …

According to the International Association for the Study of Pain (IASP) pain is characterized
as an “unpleasant sensory and emotional experience associated with actual or potential …

In the past years, cardiac mortality has decreased, but cardiac diseases are still responsible
for millions of deaths every year worldwide. Bone-marrow mesenchymal stem cells (BMSCs) …

Flufenamic acid has been known since the 1960s to have anti-inflammatory properties
attributable to the reduction of prostaglandin synthesis. Thirty years later, flufenamic acid …

Cisplatin resistance along with chemotherapy-induced neuropathic pain is an important
cause of treatment failure for many cancer types and represents an unmet clinical need …

This review aims to create an overview of the currently available results of site-directed
mutagenesis studies on transient receptor potential vanilloid type 1 (TRPV1) receptor …

Introduction: Chronic respiratory diseases, such as asthma and chronic obstructive
pulmonary disease, affect millions of patients worldwide. New therapeutic approaches to …

Increased expression of specific calcium channels in some cancers and the role of calcium
signaling in proliferation and invasion have led to studies assessing calcium channel …

Presynaptic resting Ca 2+ influences synaptic vesicle (SV) release probability. Here, we
report that a TRPV channel, Inactive (Iav), maintains presynaptic resting [Ca 2+] by …