The heterogeneity of tissue macrophages, in health and in disease, has become
increasingly transparent over the last decade. But with the plethora of data comes a natural …

There is a growing interest in understanding tissue organization, homeostasis, and
inflammation. However, despite an abundance of data, the organizing principles of tissue …

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive interstitial lung disease (ILD)
with unknown etiology in which gradual fibrotic scarring of the lungs leads to usual interstitial …

Alveoli, the lung's respiratory units, are tiny sacs where oxygen enters the bloodstream. They
are lined by flat alveolar type 1 (AT1) cells, which mediate gas exchange, and AT2 cells …

The COVID-19 pandemic has emerged as a global health emergency due to its association
with severe pneumonia and relative high mortality. However, the molecular characteristics …

INTRODUCTION Current influenza vaccines must be refreshed annually to address constant
mutations of viral hemagglutinin (HA) and neuraminidase (NA) genes because the vaccines …

Lungs are composed of a system of highly branched tubes that bring air into the alveoli,
where gas exchange takes place. The proximal and distal regions of the lung contain …

The respiratory tract is constantly exposed to the external environment, and therefore, must
be equipped to respond to and eliminate pathogens. Viral clearance and resolution of …

The epithelial surfaces of the lungs are in direct contact with the environment and are
subjected to dynamic physical forces as airway tubes and alveoli are stretched and …

Bone marrow–derived stromal cells (BMSCs) protect against acute lung injury (ALI). To
determine the role of BMSC mitochondria in this protection, we airway-instilled mice first with …