Application of CRISPR-Cas9 for Functional Analysis in A. mexicanus

I Sifuentes-Romero, E Ferrufino, JE Kowalko - Emerging Model Organisms, 2023 - Springer
Establishing genotype–phenotype relationships is critical for understanding the genetic
architecture underlying trait evolution. While functional genetic approaches have long been …

[PDF][PDF] Functional Studies of High Bone Mass Associated Genes in Both In Vitro and In Vivo Skeletal Systems

G Mcdonald - 2024 - research-information.bris.ac.uk
Osteoporosis is a prevalent age-related disease characterised by low bone mineral density
(BMD) and fragility fractures. In the clinic there is a demand for new osteo-anabolic …

[PDF][PDF] Chesi

C Medina-Gomez, BH Mullin - Pri atel, V …, 2023 - scholarlypublications …
Results SK-BMD GWAS meta-analysis. We jointly analyzed data from 21 epidemiological
studies comprising~ 43,800 individuals (Supplementary Data 1–2) and identified 79 …

Improving chemotherapeutic regimens by mitigating hearing loss as a limiting side-effect and examining transition metal ions as a ligand for zebrafish Tlr4

A Fox - 2023 - era.library.ualberta.ca
Cancer is often a debilitating disease associated with the uncontrolled growth of cells within
an organism. We have made significant strides over the past few decades in treating many …