Opportunities in the postpartum period to reduce cardiovascular disease risk after adverse pregnancy outcomes: a scientific statement from the American Heart …

J Lewey, TM Beckie, HL Brown, SD Brown… - Circulation, 2024 - Am Heart Assoc
Adverse pregnancy outcomes are common among pregnant individuals and are associated
with long-term risk of cardiovascular disease. Individuals with adverse pregnancy outcomes …

Epidemiology and management of gestational diabetes

A Sweeting, W Hannah, H Backman, P Catalano… - The Lancet, 2024 - thelancet.com
Gestational diabetes is defined as hyperglycaemia first detected during pregnancy at
glucose concentrations that are less than those of overt diabetes. Around 14% of …

Metformin plus insulin for preexisting diabetes or gestational diabetes in early pregnancy: the MOMPOD randomized clinical trial

KA Boggess, A Valint, JS Refuerzo, N Zork… - JAMA, 2023 - jamanetwork.com
Importance Insulin is recommended for pregnant persons with preexisting type 2 diabetes or
diabetes diagnosed early in pregnancy. The addition of metformin to insulin may improve …

Safety and efficacy of the new, oral, small-molecule, GLP-1 receptor agonists orforglipron and danuglipron for the treatment of type 2 diabetes and obesity: systematic …

P Karakasis, D Patoulias, K Pamporis, P Stachteas… - Metabolism, 2023 - Elsevier
Aims The present systematic review aimed to synthesize available data from recently
published randomized trials (RCTs) investigating the efficacy and safety of the novel, orally …

Placental IGFBP1 levels during early pregnancy and the risk of insulin resistance and gestational diabetes

MF Hivert, F White, C Allard, K James, S Majid… - Nature Medicine, 2024 - nature.com
Reduced insulin sensitivity (insulin resistance) is a hallmark of normal physiology in late
pregnancy and also underlies gestational diabetes mellitus (GDM). We conducted …

Drug Therapies for diabetes

R Weinberg Sibony, O Segev, S Dor, I Raz - International Journal of …, 2023 - mdpi.com
The treatment of type 2 diabetes (T2D) necessitates a multifaceted approach that combines
behavioral and pharmacological interventions to mitigate complications and sustain a high …

Randomization to a provided higher-complex-carbohydrate versus conventional diet in gestational diabetes mellitus results in similar newborn adiposity

TL Hernandez, SS Farabi, BK Fosdick, N Hirsch… - Diabetes …, 2023 - Am Diabetes Assoc
OBJECTIVE Nutrition therapy for gestational diabetes mellitus (GDM) has conventionally
focused on carbohydrate restriction. In a randomized controlled trial (RCT), we tested the …

[HTML][HTML] Gestational diabetes mellitus and COVID-19: The epidemic during the pandemic

Y Mendez, LAA Radilla, LED Chabolla… - World Journal of …, 2023 - ncbi.nlm.nih.gov
During the global coronavirus disease 2019 (COVID-19) pandemic, people worldwide have
experienced an unprecedented rise in psychological distress and anxiety. In addition to this …

Metformin versus insulin and risk of major congenital malformations in pregnancies with type 2 diabetes: a Nordic register-based cohort study

LJ Kjerpeseth, CE Cesta, K Furu, A Engeland… - Diabetes …, 2023 - Am Diabetes Assoc
OBJECTIVE To assess the risk of major congenital malformations with metformin versus
insulin in pregnancies with type 2 diabetes. RESEARCH DESIGN AND METHODS This …

Metformin in gestational diabetes mellitus: to use or not to use, that is the question

V Tocci, M Mirabelli, A Salatino, L Sicilia, S Giuliano… - Pharmaceuticals, 2023 - mdpi.com
In recent years, there has been a dramatic increase in the number of pregnancies
complicated by gestational diabetes mellitus (GDM). GDM occurs when maternal insulin …