The role of oxidative stress and natural antioxidants in ovarian aging

L Yang, Y Chen, Y Liu, Y Xing, C Miao… - Frontiers in …, 2021 - frontiersin.org
The ovarian system comprises vital organs in females and is of great significance for the
maintenance of reproductive potential and endocrine stability. Although complex …

[HTML][HTML] Current animal model systems for ovarian aging research

H Lu, L Ma, Y Zhang, Y Feng, J Zhang… - Aging and Disease, 2022 - ncbi.nlm.nih.gov
Ovarian aging leads to menopause, loss of fertility and other disorders in multiple organs,
which brings great distress to women. For ethical reasons, it is impossible to use humans as …

Iron overload in endometriosis peritoneal fluid induces early embryo ferroptosis mediated by HMOX1

S Li, Y Zhou, Q Huang, X Fu, L Zhang, F Gao, Z Jin… - Cell death …, 2021 - nature.com
Endometriosis is one of the most common disorders that causes infertility in women. Iron is
overloaded in endometriosis peritoneal fluid (PF), with harmful effects on early embryo …

[HTML][HTML] Coenzyme Q10 ameliorates the quality of postovulatory aged oocytes by suppressing DNA damage and apoptosis

M Zhang, X ShiYang, Y Zhang, Y Miao, Y Chen… - Free Radical Biology …, 2019 - Elsevier
Postovulatory aging is known to compromise the oocyte quality as well as subsequent
embryo development in many different animal models, and becomes one of the most …

In vivo and in vitro postovulatory aging: when time works against oocyte quality?

V Di Nisio, S Antonouli, P Damdimopoulou… - Journal of Assisted …, 2022 - Springer
In mammalian species an optimal fertilization window during which successful fertilization
occurs. In the majority of mammals estrus marks ovulation time and coincident with mating …

Inhibitory effects of astaxanthin on postovulatory porcine oocyte aging in vitro

BY Jia, DC Xiang, QY Shao, B Zhang, SN Liu… - Scientific Reports, 2020 - nature.com
Mammalian oocytes represent impaired quality after undergoing a process of postovulatory
aging, which can be alleviated through various effective ways such as reagent treatment …

Glutathione alleviates the cadmium exposure-caused porcine oocyte meiotic defects via eliminating the excessive ROS

C Zhou, X Zhang, Y Chen, X Liu, Y Sun, B Xiong - Environmental pollution, 2019 - Elsevier
Heavy metal cadmium (Cd) is a widespread environmental contaminant with a potential
toxicity that might adversely influence the health of experimental animals and humans. It has …

Roles of resveratrol in improving the quality of postovulatory aging oocytes in vitro

YL Sun, SB Tang, W Shen, S Yin, QY Sun - Cells, 2019 - mdpi.com
After ovulation, mammalian oocytes will undergo a time-dependent process of aging if they
are not fertilized. This postovulatory aging (POA) seriously affects the oocyte quality and …

[HTML][HTML] Ubiquinol-10 delays postovulatory oocyte aging by improving mitochondrial renewal in pigs

YJ Niu, W Zhou, ZW Nie, D Zhou, YN Xu, SA Ock… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Ubiquinol-10, the reduced form of coenzyme Q10, protects mammalian cells from oxidative
damage and enhances mitochondrial activity. However, the protective effect of ubiquinol-10 …

Effects of Acute Fluorene‐9‐Bisphenol Exposure on Mouse Oocyte in vitro Maturation and Its Possible Mechanisms

XF Jiao, QM Liang, D Wu, ZM Ding… - Environmental and …, 2019 - Wiley Online Library
Fluorene‐9‐bisphenol (BHPF), a substitute of bisphenol A (BPA) used in the production of
the so‐called “BPA‐free” plastics, has now been shown to be released from commercial …