Quantification of liver iron with MRI: state of the art and remaining challenges

D Hernando, YS Levin, CB Sirlin… - Journal of Magnetic …, 2014 - Wiley Online Library
Liver iron overload is the histological hallmark of hereditary hemochromatosis and
transfusional hemosiderosis, and can also occur in chronic hepatopathies. Iron overload can …

AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease

ME Rinella, BA Neuschwander-Tetri, MS Siddiqui… - Hepatology, 2023 - journals.lww.com
Abbreviations: AASLD, American Association for the Study of Liver Diseases; AI, artificial
intelligence; ALT, alanine aminotransferase; AST, aspartate aminotransferase; AUROC …

Imaging of the hepatobiliary tract

S Saini - New England journal of medicine, 1997 - Mass Medical Soc
Over the past two decades, ultrasonography and computed tomography (CT) have emerged
as the principal imaging methods for diagnostic examination of the liver and biliary tree. The …

Amiodarone hepatotoxicity: prevalence and clinicopathologic correlations among 104 patients

JH Lewis, RC Ranard, A Caruso, LK Jackson… - Hepatology, 1989 - journals.lww.com
The prevalence of apparent amiodarone-related hepatic injury in 104 patients followed
prospectively is compared to that reported in the literature. Asymptomatic elevation of serum …

MR imaging findings of iron overload

M Queiroz-Andrade, R Blasbalg, CD Ortega… - Radiographics, 2009 - pubs.rsna.org
Hemochromatosis can be classified as (a) primary, when it originates from a genetic
disturbance that promotes the increase of iron absorption, or (b) secondary, when it relates …

Dual-energy CT in the diagnosis and quantification of fatty liver: limited clinical value in comparison to ultrasound scan and single-energy CT, with special reference to …

MH Mendler, P Bouillet, A Le Sidaner, E Lavoine… - Journal of …, 1998 - Elsevier
Background/Aims: It has been suggested that dual-energy CT could differentiate irregular
fatty liver from other hypodense lesions. We compared dual-energy CT to ultrasound scan …

Histopathologic analysis of suspected amiodarone hepatotoxicity

JH Lewis, F Mullick, KG Ishak, RC Ranard, B Ragsdale… - Human pathology, 1990 - Elsevier
This analysis of the morphology of suspected amiodarone (AD) liver disease is based on a
study of liver specimens from 17 individuals. Changes similar to alcoholic liver injury were …

Hemochromatosis: pathophysiology, evaluation, and management of hepatic iron overload with a focus on MRI

S Golfeyz, S Lewis, IS Weisberg - Expert review of …, 2018 - Taylor & Francis
Introduction: Hereditary hemochromatosis (HH) is an autosomal recessive disorder that
occurs in approximately 1 in 200–250 individuals. Mutations in the HFE gene lead to excess …

CT and MRI of diffuse liver disease

NM Rofsky, H Fleishaker - Seminars in Ultrasound, CT and MRI, 1995 - Elsevier
CT and MRI contribute important information to the clinical evaluation of diffuse liver
disease. In some cases, these modalities can establish a diagnosis that was not ascertained …

Drug-induced steatohepatitis

V Patel, AJ Sanyal - Clinics in liver disease, 2013 - liver.theclinics.com
Hepatic steatosis is defined as fat deposition within hepatocytes (Fig. 1). It is seen
microscopically as vacuoles in a microvesicular or macrovesicular distribution …