Long non-coding RNAs (lncRNAs) have gained great attention as epigenetic regulators of
gene expression in many tissues. Increasing evidence indicates that lncRNAs, together with …

With the increasing incidence of cartilage-related diseases such as osteoarthritis (OA) and
intervertebral disc degeneration (IDD), heavier financial and social burdens need to be …

Prostate cancer (PCa) patients commonly present with osteoblastic‐type bone metastasis.
Exosomes derived from tumor cells possess biological significance and can mediate …

Implant dentures become the first choice for denture restoration in patients with tooth loss.
However, oral implants often fail in osteoporosis (OP) patients. Melatonin (MT) induces …

Both extracellular vesicles (EVs) and long noncoding RNAs (lncRNAs) have been
increasingly investigated as biomarkers, pathophysiological mediators, and potential …

Bone is a mechanosensitive organ that provides strength and support. Many bone cells,
various pathways, and signaling molecules coordinate bone metabolism and also determine …

Bone marrow mesenchymal stem cells (BMSCs) are multi-potent cell populations and are
capable of maintaining bone and body homeostasis. The stemness and potential …

lncRNA is a transcript that is more than 200 bp in length. Currently, evidence has shown that
lncRNA is of great significance in cell activity, involved in epigenetics, gene transcription …

Osteoporosis (OP) is characterized by a decrease in osteoblasts and an increase in
adipocytes in the bone marrow compartment, alongside abnormal bone/fat differentiation …

Increasing evidence uncover the essential role of long noncoding RNA (lncRNAs) in bone
metabolism and the association of lncRNA with genetic risk of osteoporosis. However …