Highlights•PIVOTALboost evaluates benefits/toxicity of pelvic node RT and focal boost dose
escalation.•Unfavourable intermediate/high risk and bulky local disease are most likely to …

Background Ultra-hypofractionated image-guided stereotactic body radiotherapy (SBRT) is
increasingly used for definitive treatment of localized prostate cancer. Magnetic resonance …

Purpose Ultrahypofractionation is appealing for prostate cancer (PCa) due to low α/β, and
increasing the dose per fraction could improve the therapeutic index. Here we report the …

Purpose Dose escalation improves localized prostate cancer disease control, and
moderately hypofractionated external beam radiation is noninferior to conventional …

Background: There are many treatment options for localized and locally advanced prostate
cancer with radiotherapy and surgery representing the main local therapeutic strategies …

With over a decade׳ s worth of clinical experience to guide stereotactic body radiotherapy
(SBRT) for the treatment of clinically localized prostate cancer (PCa), sufficient data exist for …

Purpose There is limited data on stereotactic ablative radiation therapy (SABR) in high-risk
prostate cancer (PCa), especially regarding the role of elective nodal irradiation (ENI). This …

Simple Summary Stereotactic body radiotherapy, ie, high-precision radiotherapy delivering
high doses within a few treatment sessions, is a very convenient treatment option, which has …

Background Single-dose high-dose-rate brachytherapy (HDR-BT), in a Phase-II study, was
compared to two or three fractions in intermediate and high-risk localized prostate cancer …

Purpose To report the toxicity and preliminary clinical outcomes of a prospective trial
evaluating 19-Gy, single-fraction high-dose-rate (HDR) brachytherapy for men with low-and …