Astrocytes are neural parenchymal cells that ubiquitously tile the central nervous system
(CNS). In addition to playing essential roles in healthy tissue, astrocytes exhibit an …

Remyelination is the regeneration of myelin sheaths following demyelination. This
regenerative process is critical for the re-establishment of axonal conduction velocity and …

The glial environment influences neurological disease progression, yet much of our
knowledge still relies on preclinical animal studies, especially regarding astrocyte …

The P2X7 channel is involved in the pathogenesis of various CNS diseases. An increasing
number of studies suggest its presence in neurons where its putative functions remain …

Scar formation after brain injury is still poorly understood. To further elucidate such
processes, here, we examine the interplay between astrocyte proliferation taking place …

Aging is a major risk factor for several neurodegenerative diseases and is associated with
cognitive decline. In addition to affecting neuronal function, the aging process significantly …

Astrocytes regulate brain‐wide functions and also show region‐specific differences, but little
is known about how general and region‐specific functions are aligned at the single‐cell …

Astrocytes are active participants in the performance of the Central Nervous System (CNS)
in both health and disease. During aging, astrocytes are susceptible to reactive astrogliosis …

Using retinal organoid systems, organ-like 3D tissues, relies implicitly on their robustness.
However, essential key parameters, particularly retinal growth and longer-term culture, are …

Inflammation is a complex biological response to injuries, metabolic disorders or infections.
In the brain, astrocytes play an important role in the inflammatory processes during …