The two most important aneurysm types are cerebral aneurysms and abdominal aortic
aneurysms, accounting together for over 80% of all fatal aneurysm incidences. To minimise …

Introduction: This study aims to elucidate the mechanisms underlying endothelial injury in
the context of intracranial aneurysm formation and development, which are associated with …

Intracranial aneurysms are pouch-like extrusions from the vessels at the base of the brain
which can rupture and cause a subarachnoid hemorrhage. The pathophysiological …

Objective Hemodynamic characteristics play critical roles in aneurysm initiation and growth.
This study aims to explore the effect of common hemodynamic parameters on the formation …

Primary cilium is an antenna-like and non-motile structure protruding from the apical surface
of most mammalian cells including endothelial cells lining the inner side of all the blood …

Endothelial and smooth muscle cells of the vasculature are equipped with numerous
receptors that allow them to detect and react to subtle changes in their physical environment …

Background Hemodynamic factors are believed to be closely related to IA growth. However,
the underlying pathophysiological mechanism that induces the growth sequence in tandem …

Objective This study investigated the relationship between morphology, hemodynamic
parameters, and plasma concentrations of the soluble form of tyrosine kinase receptor Axl …

Background Aneurysmal subarachnoid hemorrhage is a devastating cerebrovascular
disease associated with high morbidity and mortality. Macrophage-mediated mural …