Tissue Active Matter: Integrating Mechanics and Signaling into Dynamical Models
DB Brückner, E Hannezo - Cold Spring Harbor …, 2024 - cshperspectives.cshlp.org
The importance of physical forces in the morphogenesis, homeostatic function, and
pathological dysfunction of multicellular tissues is being increasingly characterized, both …
pathological dysfunction of multicellular tissues is being increasingly characterized, both …
Nuclear deformation and dynamics of migrating cells in 3D confinement reveal adaptation of pulling and pushing forces
S Stöberl, J Flommersfeld, MM Kreft, M Benoit… - Science …, 2024 - science.org
Eukaryotic cells show an astounding ability to remodel their shape and cytoskeleton and to
migrate through pores and constrictions smaller than their nuclear diameter. However, the …
migrate through pores and constrictions smaller than their nuclear diameter. However, the …
[PDF][PDF] Integrating frontiers: a holistic, quantum and evolutionary approach to conquering cancer through systems biology and multidisciplinary synergy
MC Casotti, DD Meira, ASS Zetum… - Frontiers in …, 2024 - researchgate.net
Cancer occurs when cells stop working for the collective and become selfish. These
changes transform the cells, giving them competitive advantages. Cancer manifestations are …
changes transform the cells, giving them competitive advantages. Cancer manifestations are …
Inferring the Langevin Equation with Uncertainty via Bayesian Neural Networks
Pervasive across diverse domains, stochastic systems exhibit fluctuations in processes
ranging from molecular dynamics to climate phenomena. The Langevin equation has served …
ranging from molecular dynamics to climate phenomena. The Langevin equation has served …
Learning dynamical models from stochastic trajectories
P Ronceray - arXiv preprint arXiv:2406.02363, 2024 - arxiv.org
The dynamics of biological systems, from proteins to cells to organisms, is complex and
stochastic. To decipher their physical laws, we need to bridge between experimental …
stochastic. To decipher their physical laws, we need to bridge between experimental …
[HTML][HTML] Learning Dynamics from Multicellular Graphs with Deep Neural Networks
H Yang, F Meyer, S Huang, L Yang, C Lungu… - ArXiv, 2024 - ncbi.nlm.nih.gov
The inference of multicellular self-assembly is the central quest of understanding
morphogenesis, including embryos, organoids, tumors, and many others. However, it has …
morphogenesis, including embryos, organoids, tumors, and many others. However, it has …
A review of active matter reviews
M Vrugt, R Wittkowski - arXiv preprint arXiv:2405.15751, 2024 - arxiv.org
In the past years, the amount of research on active matter has grown extremely rapidly, a fact
that is reflected in particular by the existence of more than 600 review articles on this topic …
that is reflected in particular by the existence of more than 600 review articles on this topic …
Nonlinear dynamics of confined cell migration--modeling and inference
The motility of eukaryotic cells is strongly influenced by their environment, with confined cells
often developing qualitatively different motility patterns from those migrating on simple two …
often developing qualitatively different motility patterns from those migrating on simple two …
The actin cortex acts as a mechanical memory of morphology in confined migrating cells
Cell migration in narrow microenvironments is a hallmark of numerous physiological
processes, involving successive cycles of confinement and release that drive significant …
processes, involving successive cycles of confinement and release that drive significant …
[PDF][PDF] The role of the physical microenvironment in cell migration and cytoskeletal force generation
J Flommersfeld - 2024 - edoc.ub.uni-muenchen.de
Cellular force generation and motility are key to embryonic development, the immune
system, wound healing, and cancer. In all these examples, cells migrate and generate forces …
system, wound healing, and cancer. In all these examples, cells migrate and generate forces …