Detection of DNA damage by space radiation in human fibroblasts flown on the International Space Station
T Lu, Y Zhang, M Wong, A Feiveson, R Gaza… - Life sciences in space …, 2017 - Elsevier
Although charged particles in space have been detected with radiation detectors on board
spacecraft since the discovery of the Van Allen Belts, reports on the effects of direct …
spacecraft since the discovery of the Van Allen Belts, reports on the effects of direct …
Cytogenetic status of interventional radiology unit workers occupationally exposed to low-dose ionising radiation: A pilot study
Interventional radiology unit workers represent one of the occupationally most exposed
populations to low-dose ionizing radiation. Since there are many uncertainties in research of …
populations to low-dose ionizing radiation. Since there are many uncertainties in research of …
Accurate gene expression-based biodosimetry using a minimal set of human gene transcripts
JD Tucker, MC Joiner, RA Thomas, WE Grever… - International Journal of …, 2014 - Elsevier
Purpose Rapid and reliable methods for conducting biological dosimetry are a necessity in
the event of a large-scale nuclear event. Conventional biodosimetry methods lack the …
the event of a large-scale nuclear event. Conventional biodosimetry methods lack the …
DNA double-strand breaks and micronuclei in human blood lymphocytes after repeated whole body exposures to 7T magnetic resonance imaging
M Fatahi, A Reddig, B Friebe, R Hartig, TJ Prihoda… - Neuroimage, 2016 - Elsevier
Purpose To examine the extent of genetic damage, assessed from deoxyribonucleic acid
(DNA) double-strand breaks (DSBs) and micronuclei (MN) in peripheral blood mononuclear …
(DNA) double-strand breaks (DSBs) and micronuclei (MN) in peripheral blood mononuclear …
Dose–response curves for analyzing of dicentric chromosomes and chromosome translocations following doses of 1000 mGy or less, based on irradiated peripheral …
Y Abe, MA Yoshida, K Fujioka, Y Kurosu… - Journal of radiation …, 2018 - academic.oup.com
In terms of biological dosimetry at the time of radiation exposure, the dicentric chromosome
(Dic) assay (DCA) is the gold standard for assessing for the acute phase and chromosome …
(Dic) assay (DCA) is the gold standard for assessing for the acute phase and chromosome …
Mitigating the risk of radiation-induced cancers: limitations and paradigms in drug development
SS Yoo, TJ Jorgensen, AR Kennedy… - Journal of …, 2014 - iopscience.iop.org
Abstract The United States radiation medical countermeasures (MCM) programme for
radiological and nuclear incidents has been focusing on developing mitigators for the acute …
radiological and nuclear incidents has been focusing on developing mitigators for the acute …
Validation of the cytokinesis-block micronucleus assay using imaging flow cytometry for high throughput radiation biodosimetry
MA Rodrigues, LA Beaton-Green, RC Wilkins - Health Physics, 2016 - journals.lww.com
The cytokinesis-block micronucleus assay can be employed in triage radiation biodosimetry
to determine the dose of radiation to an exposed individual by quantifying the frequency of …
to determine the dose of radiation to an exposed individual by quantifying the frequency of …
Development of a high-throughput and miniaturized cytokinesis-block micronucleus assay for use as a biological dosimetry population triage tool
SW Lue, M Repin, R Mahnke… - Radiation …, 2015 - meridian.allenpress.com
Biodosimetry is an essential tool for providing timely assessments of radiation exposure. For
a large mass-casualty event involving exposure to ionizing radiation, it is of utmost …
a large mass-casualty event involving exposure to ionizing radiation, it is of utmost …
Micronucleus assay for predicting side effects of radiotherapy for cervical cancer
E Borges da Silva, M Brayner Cavalcanti… - Biotechnic & …, 2021 - Taylor & Francis
Radiotherapy (RT) is an important treatment for cervical cancer. The quality of life of patients
undergoing RT may be compromised during and following treatment by nausea, diarrhea …
undergoing RT may be compromised during and following treatment by nausea, diarrhea …
Mechanisms by which genotoxins cause micronuclei and other nuclear anomalies
M Fenech - 2019 - books.rsc.org
Normal eukaryotic cells contain a single nucleus. However, abnormal small nuclei known as
micronuclei (MN), additional to the main nucleus, may occur in cells that are exposed to …
micronuclei (MN), additional to the main nucleus, may occur in cells that are exposed to …