Background Cisplatin (CN) is considered as a cytotoxic agent and DNA synthesis inhibitor.
D-Ribose-l-Cysteine (DRLC) is an active ingredient of riboceine, help cells to produce …

This study was conducted to evaluate the protective role of Pleurotus eryngii extract (PE)
and Pleurotus eryngii extract‐loaded chitosan nanoparticles (PE‐CSNP) against …

Male infertility is a common side effect of doxorubicin (DOX) that substantially impairs the
quality of life of young cancer survivors. Therefore, the current work was designed to …

Despite its deleterious effect on healthy cells and highly regenerating cells such as
spermatozoa, Doxorubicin (DOX) is still one of the most used anticancer drugs in the last …

Doxorubicin (DOX) is a chemotherapy agent associated with adverse effects on male
reproductive health. Chlorella vulgaris (ChV) is a potent natural antioxidant with promising …

Melatonin is a pineal hormone that regulates testicular activity (ie steroidogenesis and
spermatogenesis) through two complementary mechanisms, indirect effects exerted via the …

Objectives To study the effects of silymarin in various forms of applications on the molecular
mechanism (s) of doxorubicin-induced testicular toxicity in male rats. Methods Following …

The search for methods that identify early toxicity, induced by chemotherapy, is urgent.
Changes in the biodistribution of radiopharmaceuticals could give information on early …

Oxidative stress is the main factor in Doxorubicin (DXR) induced toxicity. Rats received
either DXR (3 mg/kg, ip) on day 1, 7, 14, 21, 28 or Solanum torvum extract (100 mg/kg and …

Chlorambucil (4‐[4‐[bis (2‐chloroethyl) amino] phenyl] butanoic acid) is an alkylating agent,
indicated in chronic lymphocytic leukaemia. Kolaviron (KV), a biflavonoid complex from …