Next-generation cancer organoids

BL LeSavage, RA Suhar, N Broguiere, MP Lutolf… - Nature materials, 2022 - nature.com
Organotypic models of patient-specific tumours are revolutionizing our understanding of
cancer heterogeneity and its implications for personalized medicine. These advancements …

Carbohydrate-based macromolecular biomaterials

L Su, Y Feng, K Wei, X Xu, R Liu, G Chen - Chemical Reviews, 2021 - ACS Publications
Carbohydrates are the most abundant and one of the most important biomacromolecules in
Nature. Except for energy-related compounds, carbohydrates can be roughly divided into …

Immune cell Membrane‐Coated biomimetic nanoparticles for targeted cancer therapy

F Oroojalian, M Beygi, B Baradaran, A Mokhtarzadeh… - Small, 2021 - Wiley Online Library
Nanotechnology has provided great opportunities for managing neoplastic conditions at
various levels, from preventive and diagnostic to therapeutic fields. However, when it comes …

Capturing functional two-dimensional nanosheets from sandwich-structure vermiculite for cancer theranostics

X Ji, L Ge, C Liu, Z Tang, Y Xiao, W Chen, Z Lei… - Nature …, 2021 - nature.com
Abstract Clay-based nanomaterials, especially 2: 1 aluminosilicates such as vermiculite,
biotite, and illite, have demonstrated great potential in various fields. However, their …

Delivery technologies for cancer immunotherapy

RS Riley, CH June, R Langer, MJ Mitchell - Nature reviews Drug …, 2019 - nature.com
Immunotherapy has become a powerful clinical strategy for treating cancer. The number of
immunotherapy drug approvals has been increasing, with numerous treatments in clinical …

Advances in biomaterials for drug delivery

OS Fenton, KN Olafson, PS Pillai… - Advanced …, 2018 - Wiley Online Library
Advances in biomaterials for drug delivery are enabling significant progress in biology and
medicine. Multidisciplinary collaborations between physical scientists, engineers, biologists …

Modeling physiological events in 2D vs. 3D cell culture

K Duval, H Grover, LH Han, Y Mou… - …, 2017 - journals.physiology.org
Cell culture has become an indispensable tool to help uncover fundamental biophysical and
biomolecular mechanisms by which cells assemble into tissues and organs, how these …

Edge modification facilitated heterogenization and exfoliation of two-dimensional nanomaterials for cancer catalytic therapy

L Chen, Z Mao, Y Wang, Y Kang, Y Wang, L Mei… - Science …, 2022 - science.org
The rapid recombination of electron-hole pairs and limited substrates are the most critical
factors astricting the effect of catalytic therapy. Thus, two-dimensional interplanar …

Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment

G Huang, F Li, X Zhao, Y Ma, Y Li, M Lin, G Jin… - Chemical …, 2017 - ACS Publications
The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

Bioresponsive materials

Y Lu, AA Aimetti, R Langer, Z Gu - Nature Reviews Materials, 2016 - nature.com
Abstract 'Smart'bioresponsive materials that are sensitive to biological signals or to
pathological abnormalities, and interact with or are actuated by them, are appealing …