Cell-free DNA (cfDNA) refers to short fragments of acellular nucleic acids detectable in
almost all body fluids, including blood, and is involved in various physiological and …

Neoplasms are microcosms of evolution. Within a neoplasm, a mosaic of mutant cells
compete for space and resources, evade predation by the immune system and can even …

Metastatic breast cancer is usually diagnosed after becoming symptomatic, at which point it
is rarely curable. Cell‐free circulating tumor DNA (ct DNA) contains tumor‐specific …

The recent flood of reports using real-time Q-PCR testifies to the transformation of this
technology from an experimental tool into the scientific mainstream. Many of the applications …

Real-time quantitative PCR allows the sensitive, specific and reproducible quantitation of
nucleic acids. Since its introduction, real-time quantitative PCR has revolutionized the field …

It is well known that malignant cells circulate in the bloodstream of patients with solid tumors.
However, the biological significance of circulating tumor cells (CTCs) and the clinical …

Isolation of circulating tumor cells (CTCs) from blood has long been a challenge due to the
rarity and heterogeneity of these cells. Detection technologies have predominantly focused …

Abstract The t (14; 18) translocation is a common genetic aberration that can be seen as an
early step in pathogenesis of follicular lymphoma (FL). The significance of low level …

In recent years, considerable progress has been made in understanding the biology of
canine lymphoma with resultant enhanced classification schemes and the possibility of …

The t (14; 18)-translocation can frequently detected in the peripheral blood and tissue
samples from healthy individuals. If the sensitivity of the assay used for the detection is high …