The blood-brain barrier (BBB) is essential for maintaining brain homeostasis and low
permeability. BBB maintenance is important in the central nervous system (CNS) because …

The blood-brain barrier (BBB) and blood-cerebrospinal fluid (BCSF) barriers are critical
determinants of CNS homeostasis. Additionally, the BBB and BCSF barriers are formidable …

This report reviews the anatomical, pathophysiological, and clinical aspects of radiation
injury to the central nervous system (CNS). Despite the lack of pathognomonic …

Human and macaque retinae have similar retinal vascular anatomy. The general features of
the retinal vascular anatomy of these two primates have much in common with more widely …

Studies of neonatal neural pathologies and development of appropriate therapeutics are
hampered by a lack of relevant in vitro models of neonatal blood-brain barrier (BBB). To …

Elevation of intraocular pressure (IOP) is a major risk factor for neurodegeneration in
glaucoma. Glial cells, which play an important role in normal functioning of retinal neurons …

Some recombinant adeno-associated viruses (rAAVs) can cross the neonatal blood–brain
barrier (BBB) and efficiently transduce cells of the central nervous system (CNS). However …

Clinical trial results of peripheral B cell depletion indicate abnormal proinflammatory B cell
properties, and particularly antibody-independent functions, contribute to relapsing MS …

While patrolling the body in search of foreign antigens, naive lymphocytes continuously
circulate from the blood, through the lymph nodes, into the lymphatic vessels and back to the …

High endothelial venules (HEVs? are specialized postcapillary venules found in lymphoid
tissues that support high levels of lymphocyte extravasation from the blood. Here, Jean …