Repurposing of drugs: An attractive pharmacological strategy for cancer therapeutics
A Kirtonia, K Gala, SG Fernandes, G Pandya… - Seminars in cancer …, 2021 - Elsevier
Human malignancies are one of the major health-related issues though out the world and
anticipated to rise in the future. The development of novel drugs/agents requires a huge …
anticipated to rise in the future. The development of novel drugs/agents requires a huge …
Immune system in cancer radiotherapy: Resistance mechanisms and therapy perspectives
K Mortezaee, M Najafi - Critical reviews in oncology/hematology, 2021 - Elsevier
Radiotherapy is a common modality for more than half of cancer patients. Classically,
radiation is known as a strategy to kill cancer cells via direct interaction with DNA or …
radiation is known as a strategy to kill cancer cells via direct interaction with DNA or …
The role of the estrogen pathway in the tumor microenvironment
NJ Rothenberger, A Somasundaram… - International journal of …, 2018 - mdpi.com
Estrogen receptors are broadly expressed in many cell types involved in the innate and
adaptive immune responses, and differentially regulate the production of cytokines. While …
adaptive immune responses, and differentially regulate the production of cytokines. While …
Mouse tumor models for advanced cancer immunotherapy
Recent advances in the development of new methods of cancer immunotherapy require the
production of complex cancer animal models that reliably reflect the complexity of the tumor …
production of complex cancer animal models that reliably reflect the complexity of the tumor …
Sex and gender differences in lung cancer and chronic obstructive lung disease
JM Siegfried - Endocrinology, 2022 - academic.oup.com
Two highly prevalent pulmonary diseases, lung cancer and chronic obstructive lung disease
(COPD), show both sex and gender differences in their presentations and outcomes. Sex …
(COPD), show both sex and gender differences in their presentations and outcomes. Sex …
[HTML][HTML] Influence of estrogen on the NSCLC microenvironment: a comprehensive picture and clinical implications
T Smida, TC Bruno, LP Stabile - Frontiers in Oncology, 2020 - frontiersin.org
Lung cancer mortality represents the leading cause of cancer related deaths in the United
States and worldwide. Almost half of these deaths occur in female patients, making lung …
States and worldwide. Almost half of these deaths occur in female patients, making lung …
Targeting inflammation in non-small cell lung cancer through drug repurposing
Lung cancer is the most common cause of cancer-related deaths. Lung cancers can be
classified as small-cell (SCLC) or non-small cell (NSCLC). About 84% of all lung cancers …
classified as small-cell (SCLC) or non-small cell (NSCLC). About 84% of all lung cancers …
Targets for improving tumor response to radiotherapy
K Mortezaee, W Parwaie, E Motevaseli… - International …, 2019 - Elsevier
Radiotherapy is one of the most common treatment modalities for controlling a wide range of
tumors. However, it has been shown that radiotherapy alone is unable to completely …
tumors. However, it has been shown that radiotherapy alone is unable to completely …
Estrogens, cancer and immunity
I Orzołek, J Sobieraj, J Domagała-Kulawik - Cancers, 2022 - mdpi.com
Simple Summary In this review, we present current knowledge of sex hormones in the
process of development of malignant diseases. The impact of sex hormones on immune …
process of development of malignant diseases. The impact of sex hormones on immune …
Chronic inflammation and cancer; the two sides of a coin
The correlation between chronic inflammation and cancer was initially identified in the 19th
century. Biomolecules like interleukins, chemokines, tumor necrosis factors, growth factors …
century. Biomolecules like interleukins, chemokines, tumor necrosis factors, growth factors …