Synthesis, crystal structure, and solubility study of a supramolecular assembly cocrystal formed by levofloxacin and nicotinic acid
M Li, Z Yang, Y Zhang, H Xu, S Zhang, J Sun… - Journal of Molecular …, 2022 - Elsevier
A novel chemical structure named pharmaceutical cocrystal was synthesized with the
purpose to enhance the solubility of levofloxacin (LVFX). Nicotinic acid (NA) was selected as …
purpose to enhance the solubility of levofloxacin (LVFX). Nicotinic acid (NA) was selected as …
Preparation of itraconazole nanoparticles by anti-solvent precipitation method using a cascaded microfluidic device and an ultrasonic spray drier
We propose a cascaded device connecting microfluidic nanoprecipitation and ultrasonic
spray drying to produce dry drug nanoparticles directly. Itraconazole (ITZ) was chosen as a …
spray drying to produce dry drug nanoparticles directly. Itraconazole (ITZ) was chosen as a …
Exploring the Solid-State Landscape of Atropisomers in (±)-Lesinurad: Insights into Crystallographic Analysis, Transformation Behavior, and Dissolution Performance
X Zhou, J Ye, Z Jin, Y Kang, X Hu - Crystal Growth & Design, 2024 - ACS Publications
Axial chirality is a unique form of chirality characterized by restricted rotation around a
covalent bond due to steric or electronic hindrances, a phenomenon known as …
covalent bond due to steric or electronic hindrances, a phenomenon known as …
Three new orbifloxacin multicomponent crystal forms towards pharmaceutical improvement
OMM Santos, JTJ Freitas, M Bitencourt… - Journal of Molecular …, 2020 - Elsevier
Orbifloxacin (ORBI) is a third-generation synthetic fluoroquinolone used as an antimicrobial
veterinary drug for the treatment of gastrointestinal and respiratory infections. Structural …
veterinary drug for the treatment of gastrointestinal and respiratory infections. Structural …
[PDF][PDF] Fabrication and solid state characterization of ticagrelor co-crystals with improved solubility and dissolution
G Pai, MB Sathyanarayana - BDL, 2017 - researchgate.net
In the present study a new co-crystal of Ticagrelor with L-Tartaric acid has been prepared
with improved solubility. Ticagrelor is a class VI drug with poor solubility and permeability; …
with improved solubility. Ticagrelor is a class VI drug with poor solubility and permeability; …
Energy framework and solubility: a new predictive model in the evaluation of the structure–property relationship of pharmaceutical solid forms
JTJ Freitas, LF Diniz, DS Gomes, PMAF de Paula… - …, 2022 - pubs.rsc.org
The active pharmaceutical ingredient (API) is a drug product's biologically active chemical
substance that produces the desired therapeutic effects. Most APIs are small organic …
substance that produces the desired therapeutic effects. Most APIs are small organic …
[PDF][PDF] Use of glutaric acid to improve the solubility and dissolution profile of glipizide through pharmaceutical cocrystallization
F Batool, M Ahmad, MU Minhas, Q Khalid… - Acta Poloniae …, 2019 - bibliotekanauki.pl
The purpose of current study was to improve the solubility and dissolution profile of BCS
class-II drug Glipizide using glutaric acid as a coformer via various cocrystalization …
class-II drug Glipizide using glutaric acid as a coformer via various cocrystalization …
[PDF][PDF] Evaluation of Physicochemical Parameters of Piroxicam 20 mg Tablets Commercially Available in District Larkana, Sindh
The objective of this study is to evaluate the physicochemical parameters of Piroxicam 20
mg Tablet brands. A comparative qualitative research study was conducted for a period of …
mg Tablet brands. A comparative qualitative research study was conducted for a period of …
Estudo estrutural e físico-químico de formas sólidas da buclizina
MB SILVA - 2019 - bdtd.unifal-mg.edu.br
RESUMO A busca por Ingredientes Farmaceuticamente Ativos (IFA), de maior solubilidade,
tem motivado vários estudos envolvendo Engenharia de Cristais de moléculas de fármacos …
tem motivado vários estudos envolvendo Engenharia de Cristais de moléculas de fármacos …