Restriction of HIV-1 and other retroviruses by TRIM5
BK Ganser-Pornillos, O Pornillos - Nature Reviews Microbiology, 2019 - nature.com
Mammalian cells express a variety of innate immune proteins—known as restriction factors—
which defend against invading retroviruses such as HIV-1. Two members of the tripartite …
which defend against invading retroviruses such as HIV-1. Two members of the tripartite …
HIV-1 capsid variability: viral exploitation and evasion of capsid-binding molecules
A Saito, M Yamashita - Retrovirology, 2021 - Springer
The HIV-1 capsid, a conical shell encasing viral nucleoprotein complexes, is involved in
multiple post-entry processes during viral replication. Many host factors can directly bind to …
multiple post-entry processes during viral replication. Many host factors can directly bind to …
Crystal structure of TRIM20 C-terminal coiled-coil/B30. 2 fragment: implications for the recognition of higher order oligomers
C Weinert, D Morger, A Djekic, MG Grütter, PRE Mittl - Scientific reports, 2015 - nature.com
Many tripartite motif-containing (TRIM) proteins, comprising RING-finger, B-Box and coiled-
coil domains, carry additional B30. 2 domains on the C-terminus of the TRIM motif and are …
coil domains, carry additional B30. 2 domains on the C-terminus of the TRIM motif and are …
Characterization of a large cluster of influenza A (H1N1) pdm09 viruses cross-resistant to oseltamivir and peramivir during the 2013-2014 influenza season in Japan
E Takashita, M Kiso, S Fujisaki… - Antimicrobial agents …, 2015 - Am Soc Microbiol
ABSTRACT Between September 2013 and July 2014, 2,482 influenza 2009 pandemic A
(H1N1)[A (H1N1) pdm09] viruses were screened in Japan for the H275Y substitution in their …
(H1N1)[A (H1N1) pdm09] viruses were screened in Japan for the H275Y substitution in their …
Toward a macaque model of HIV-1 infection: Roadblocks, progress, and future strategies
The human-specific tropism of Human Immunodeficiency Virus Type 1 (HIV-1) has
complicated the development of a macaque model of HIV-1 infection/AIDS that is suitable for …
complicated the development of a macaque model of HIV-1 infection/AIDS that is suitable for …
The three-fold axis of the HIV-1 capsid lattice is the species-specific binding interface for TRIM5α
D Morger, F Zosel, M Bühlmann, S Züger… - Journal of …, 2018 - Am Soc Microbiol
Rhesus TRIM5α (rhTRIM5α) potently restricts replication of human immunodeficiency virus
type 1 (HIV-1). Restriction is mediated through direct binding of the C-terminal B30. 2 …
type 1 (HIV-1). Restriction is mediated through direct binding of the C-terminal B30. 2 …
In silico Analysis of HIV-1 Env-gp120 Reveals Structural Bases for Viral Adaptation in Growth-Restrictive Cells
M Yokoyama, M Nomaguchi, N Doi, T Kanda… - Frontiers in …, 2016 - frontiersin.org
Variable V1/V2 and V3 loops on human immunodeficiency virus type 1 (HIV-1) envelope-
gp120 core play key roles in modulating viral competence to recognize two infection …
gp120 core play key roles in modulating viral competence to recognize two infection …
Involvement of a Rarely Used Splicing SD2b Site in the Regulation of HIV-1 vif mRNA Production as Revealed by a Growth-Adaptive Mutation
T Koma, N Doi, BQ Le, T Kondo, M Ishizue, C Tokaji… - Viruses, 2023 - mdpi.com
We have previously reported an HIV-1 mutant designated NL-Y226tac that expresses Vif at
an ultra-low level, being replication-defective in high-APOBEC3G cells, such as H9. It carries …
an ultra-low level, being replication-defective in high-APOBEC3G cells, such as H9. It carries …
A neutralization assay based on pseudo-typed lentivirus with SARS CoV-2 spike protein in ACE2-expressing CRFK cells
Y Pısıl, H Shida, T Miura - Pathogens, 2021 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly pathogenic
zoonotic virus that spreads rapidly. In this work, we improve the hitherto existing …
zoonotic virus that spreads rapidly. In this work, we improve the hitherto existing …
Impact of TRIM5α in vivo
EE Nakayama, T Shioda - Aids, 2015 - journals.lww.com
Abstract HIV type 1 (HIV-1) has a very narrow host range that is limited to humans and
chimpanzees. HIV-1 cannot replicate well in Old World monkey cells such as rhesus and …
chimpanzees. HIV-1 cannot replicate well in Old World monkey cells such as rhesus and …