REM Behavior Disorder: Implications for PD Therapeutics

JS Feuerstein, A Amara - Current Neurology and Neuroscience Reports, 2023 - Springer
Purpose Rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia that
occurs during REM sleep, characterized by REM sleep without atonia (RSWA) and dream …

Role of the Night-Time Systemic Processes and the Astrocyte Tryptophan-Melatonin Pathway in the Regulation of α-Synuclein and Wider Parkinson's Disease …

G Anderson - 2023 - preprints.org
An array of diverse processes and factors have been linked to the pathoetiology and
pathophysiology of Parkinson's disease (PD), including systemic CNS factors. This article …

Alteration of circadian sleep-wake rhythm and salivary melatonin secretion in idiopathic/isolated REM sleep behavior disorder: Preliminary evidence

M Carpi, M Fernandes, I Risino, R Benedetti, G Testone… - Sleep Medicine, 2024 - Elsevier
Abstract Objective/Background Idiopathic/isolated REM sleep behavior disorder (iRBD) is
widely regarded as an early sign of neurodegeneration leading to synucleinopathies. While …

[HTML][HTML] Neuroprotective Potential of Melatonin: Evaluating Therapeutic Efficacy in Alzheimer's and Parkinson's Diseases

NC Talbot, PM Luther, NJ Spillers, AR Ragland… - Cureus, 2023 - ncbi.nlm.nih.gov
Decreased melatonin levels have been linked to both Alzheimer's disease (AD) and
Parkinson's disease (PD), which are the two most prevalent neurodegenerative disorders …