Pancreatic neuroendocrine neoplasms: 2020 update on pathologic and imaging findings and classification

L Khanna, SR Prasad, A Sunnapwar, S Kondapaneni… - Radiographics, 2020 - pubs.rsna.org
Pancreatic neuroendocrine neoplasms (panNENs) are heterogeneous neoplasms with
neuroendocrine differentiation that show characteristic clinical, histomorphologic, and …

Neuroendocrine neoplasms of the small bowel and pancreas

AK Clift, M Kidd, L Bodei, C Toumpanakis… - …, 2020 - karger.com
The traditionally promulgated perspectives of neuroendocrine neoplasms (NEN) as rare,
indolent tumours are blunt and have been outdated for the last 2 decades. Clear increments …

[HTML][HTML] Integrated genomic and clinicopathologic approach distinguishes pancreatic grade 3 neuroendocrine tumor from neuroendocrine carcinoma and identifies a …

SE Umetsu, S Kakar, O Basturk, GE Kim, D Chatterjee… - Modern Pathology, 2023 - Elsevier
Distinguishing grade 3 pancreatic neuroendocrine tumor (G3 PanNET) from neuroendocrine
carcinoma (PanNEC) is a known diagnostic challenge, and accurate classification is critical …

Molecular profiling of neuroendocrine tumours to predict response and toxicity to peptide receptor radionuclide therapy

L Bodei, H Schöder, RP Baum, K Herrmann… - The lancet …, 2020 - thelancet.com
Peptide receptor radionuclide therapy (PRRT) is a type of radiotherapy that targets peptide
receptors and is typically used for neuroendocrine tumours (NETs). Some of the key …

Novel therapeutic strategies targeting telomere maintenance mechanisms in high-risk neuroblastoma

SL George, V Parmar, F Lorenzi, LV Marshall… - Journal of Experimental …, 2020 - Springer
The majority of high-risk neuroblastomas can be divided into three distinct molecular
subgroups defined by the presence of MYCN amplification, upstream TERT rearrangements …

Biomarkers for pancreatic neuroendocrine neoplasms (PanNENs) management—an updated review

M Bocchini, F Nicolini, S Severi, A Bongiovanni… - Frontiers in …, 2020 - frontiersin.org
Pancreatic neuroendocrine tumors (PanNENs) are rare sporadic cancers or develop as part
of hereditary syndromes. PanNENs can be both functioning and non-functioning based on …

Peptide receptor radionuclide therapy for the treatment of pancreatic neuroendocrine tumors: recent insights

JS Starr, MB Sonbol, TJ Hobday, A Sharma… - OncoTargets and …, 2020 - Taylor & Francis
Peptide receptor radionuclide therapy (PRRT) is a paradigm shifting approach to the
treatment of neuroendocrine tumors. Although there are no prospective randomized trials …

Molecular pathology of well-differentiated gastro-entero-pancreatic neuroendocrine tumors

SL Asa, S La Rosa, O Basturk, V Adsay, M Minnetti… - Endocrine …, 2021 - Springer
Well differentiated neuroendocrine tumors (NETs) arising in the gastrointestinal and
pancreaticobiliary system are the most common neuroendocrine neoplasms. Studies of the …

Neuroendocrine neoplasms: current and potential diagnostic, predictive and prognostic markers

AD Herrera-Martínez, LJ Hofland… - Endocrine-related …, 2019 - erc.bioscientifica.com
Some biomarkers for functioning and non-functioning neuroendocrine neoplasms (NENs)
are currently available. Despite their application in clinical practice, results should be …

[HTML][HTML] Liquid biopsy and preclinical tools for advancing diagnosis and treatment of patients with pancreatic neuroendocrine neoplasms

B Smolkova, A Kataki, J Earl, I Ruz-Caracuel… - Critical Reviews in …, 2022 - Elsevier
Pancreatic neuroendocrine neoplasms (pNENs) are rare cancers with broad challenges for
their management. The main clinical obstacles are the high rate of patients diagnosed at …