Therapeutic strategies targeting the endothelial glycocalyx

DR Machin, M Sabouri, X Zheng… - Current Opinion in …, 2023 - journals.lww.com
We conclude that the glycocalyx is degraded in a variety of health conditions, although it
remains to be determined whether glycocalyx degradation plays a causal role in disease …

[HTML][HTML] Type 1 Diabetes and COVID-19: A Literature Review and Possible Management

K Kashfi, N Anbardar, A Asadipooya… - International Journal of …, 2023 - ncbi.nlm.nih.gov
Results A total of 25 manuscripts out of 304 identified studies were selected. There were 15
(60%) multicenter or nationwide studies. The data about the incidence rate of T1D …

[HTML][HTML] Interleukin-6 drives endothelial glycocalyx damage in COVID-19 and bacterial sepsis

CC Drost, A Rovas, I Osiaevi, K Schughart, A Lukasz… - Angiogenesis, 2024 - Springer
Damage of the endothelial glycocalyx (eGC) plays a central role in the development of
vascular hyperpermeability and organ damage during systemic inflammation. However, the …

[HTML][HTML] The Effect of Potassium Canrenoate (Mineralocorticoid Receptor Antagonist) on the Markers of Inflammation in the Treatment of COVID-19 Pneumonia and …

I Karolak, R Hrynkiewicz… - International Journal of …, 2023 - mdpi.com
In March 2020, the World Health Organization (WHO) announced a global pandemic of
coronavirus disease 2019 (COVID-19) that presented mainly as an acute infection of the …

Combination of spironolactone and DPP-4 inhibitors for treatment of SARS-CoV-2 infection: a literature review

K Asadipooya, A Asadipooya, R Adatorwovor - Archives of Virology, 2024 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is still causing hospitalization and death,
and vaccination appears to become less effective with each emerging variant. Spike, non …

[HTML][HTML] Prolonged Door-to-Balloon Time Leads to Endothelial Glycocalyx Damage and Endothelial Dysfunction in Patients with ST-Elevation Myocardial Infarction

C Vahldieck, B Fels, S Löning, L Nickel, J Weil… - Biomedicines, 2023 - mdpi.com
Damage to the endothelial glycocalyx (eGC) has been reported during acute ischemic
events like ST-elevation myocardial infarction (STEMI). In STEMI, a door-to-balloon time …

Integrative Systems Immunology Analysis Reveals Elevated Anti-AGTR1 Levels with Accumulating COVID-19 Symptoms

DLM Fonseca Sr, M Japel, IS Filgueiras, GC Baiochi… - medRxiv, 2024 - medrxiv.org
The coronavirus disease 2019 (COVID-19) displays a broad spectrum of symptoms, with the
underlying reasons for this variability still not fully elucidated. Our study investigates the …

Steroid hormone receptors and regulation of ACE2 and COVID-19 disease outcomes

M Young, K Chapman - Stress: Immunology and Inflammation, 2024 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a worldwide
pandemic and social and economic upheaval. To date, SARS-CoV-2 has infected more than …

Type1 Diabetes and COVID-19: A Systematic Review and Possible Management

K Kashfi, N Anbardar, A Asadipooya, K Asadipooya - 2023 - preprints.org
Introduction SARS-CoV-2 infection normally damages respiratory system but may likewise
impair endocrine organs' function. Thyroid dysfunction and hyperglycemia are common …

Prolonged Door-to-Balloon time leads to glycocalyx damage and endothelial dysfunction in patients with ST-Elevation Myocardial Infarction and cardiogenic shock

C Vahldieck, B Fels, S Löning, L Nickel, J Weil… - 2023 - researchsquare.com
Background Damage to the endothelial glycocalyx (eGC) and endothelial dysfunction have
been reported to develop during cardiac ischemia-and-reperfusion injury (IRI), such as ST …