Endometriosis is a chronic systemic disease: clinical challenges and novel innovations

HS Taylor, AM Kotlyar, VA Flores - The Lancet, 2021 - thelancet.com
Endometriosis is a common disease affecting 5–10% of women of reproductive age globally.
However, despite its prevalence, diagnosis is typically delayed by years, misdiagnosis is …

The use of D-chiro-Inositol in clinical practice

R Gambioli, G Forte, C Aragona… - European Review for …, 2021 - iris.uniroma1.it
OBJECTIVE: D-chiro-Inositol has been widely used in clinical practice to induce ovulation in
women with polycystic ovary syndrome. Only recent evidence established that this molecule …

Ulipristal acetate for treatment of premenstrual dysphoric disorder: a proof-of-concept randomized controlled trial

E Comasco, H Kopp Kallner, M Bixo… - American Journal of …, 2021 - Am Psychiatric Assoc
Objective: Premenstrual dysphoric disorder (PMDD) is a common mood disorder,
characterized by distressing affective, behavioral, and somatic symptoms in the late luteal …

Conservative management of uterine fibroid-related heavy menstrual bleeding and infertility: time for a deeper mechanistic understanding and an individualized …

MM Dolmans, L Cacciottola, J Donnez - Journal of clinical medicine, 2021 - mdpi.com
(1) Background: Uterine fibroids are the most common form of benign uterine tumors,
causing heavy menstrual bleeding (HMB), pelvic pain, infertility and pressure symptoms …

New pharmacological approaches to the management of premenstrual dysphoric disorder

I Sundström-Poromaa, E Comasco - CNS drugs, 2023 - Springer
Premenstrual symptoms are experienced by many female individuals during their fertile age.
Premenstrual dysphoric disorder (PMDD), a sex-specific mood disorder, affects about 5% of …

Society of Family Planning clinical recommendation: emergency contraception

J Salcedo, K Cleland, D Bartz, I Thompson - Contraception, 2023 - Elsevier
Emergency contraception (EC) refers to several contraceptive options that can be used
within a few days after unprotected or under protected intercourse or sexual assault to …

Uterine fibroid management: Today and tomorrow

MM Dolmans, J Donnez, L Fellah - Journal of Obstetrics and …, 2019 - Wiley Online Library
Current treatments for fibroids are mainly surgical and expensive, so alternatives need to be
found. It is, therefore, vital to develop and evaluate alternatives to surgical procedures …

Hormone therapy for intramural myoma-related infertility from ulipristal acetate to GnRH antagonist: a review

J Donnez, MM Dolmans - Reproductive biomedicine online, 2020 - Elsevier
Uterine fibroids may cause infertility, depending on their size and location according to the
International Federation of Gynecology and Obstetrics classification. In this review, infertility …

The evolving role of natural compounds in the medical treatment of uterine fibroids

M Ciebiera, M Ali, L Prince, T Jackson-Bey… - Journal of clinical …, 2020 - mdpi.com
Uterine fibroids (UFs) remain a significant health issue for many women, with a
disproportionate impact on women of color, likely due to both genetic and environmental …

Elagolix in the treatment of heavy menstrual bleeding associated with uterine fibroids in premenopausal women

M Ali, S AR, A Al Hendy - Expert review of clinical pharmacology, 2021 - Taylor & Francis
ABSTRACT Introduction Uterine fibroids (UFs) are the most common benign tumor arising
from myometrium of reproductive age women, with significant financial burden estimated in …